RECRUITING

Positive Minds Strong Joints for Knee Osteoarthritis

Conditions

Osteoarthritis, Knee chronic pain depression anxiety exercise cognitive behavioral therapy Black adults

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The aim of this research study is to test the feasibility of a physical and mental health intervention (Positive Minds, Strong Joints or PMSJ) for Black adults with knee osteoarthritis (OA).

Official Title

Physical and Mental Health Intervention for Black Adults with Knee Osteoarthritis: a Feasibility Study

Quick Facts

Study Start:2025-02-17

Study Completion:2026-12-30

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06493903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Age≥50 * BMI ≤ 40 kg/m2 * Self-identify as Black (including African American) * Knee pain ≥4/10 on a 11 numeric scale over the past week * Scored 5 or more on either the Patient Health Questionnaire (PHQ-9) and/or the Generalized Anxiety Disorder 7-item Scale (GAD-7) * Can speak and understand English at a sufficient level to understand the study procedures and informed consent * Available for study duration * Available to attend in-person intervention sessions at the community location * Able to attend remote sessions * Knee, hip or ankle replacement * Intra-articular corticosteroid or hyaluronic acid knee injection within 3 months * Knee surgery within past 6 months * Currently receiving or received within 3-months any PT for knee OA * Currently receiving or received within 3 months any mental health intervention (excluding pharmacologic treatments) * Planning to initiate physical therapy for joint or low back pain in the next 3months * Planning to initiate any mental health treatment (excluding pharmacologic treatments) in the next 1 month. * Systemic inflammatory arthritis (e.g., rheumatoid arthritis) * Neurologic conditions (e.g., stroke, Parkinson's disease, etc.) * Contraindications to starting an exercise program. * Suspected substance abuse * Lack capacity to consent * Pregnancy (self-report) * Participation in another clinical trial for any joint or muscle pain * Planning for a major surgery in the next 6 months * Having high risk mental health symptoms (active suicidality, bipolar disorder, mania, psychosis, schizophrenia) * Receiving chemotherapy or radiation therapy for cancer (except non-melanoma skin cancer)	Pregnancy or breastfeeding Severe psychiatric disorders Active substance abuse Unstable medical conditions Inability to comply with study requirements

Inclusion Criteria

Exclusion Criteria

* Age≥50
* BMI ≤ 40 kg/m2
* Self-identify as Black (including African American)
* Knee pain ≥4/10 on a 11 numeric scale over the past week
* Scored 5 or more on either the Patient Health Questionnaire (PHQ-9) and/or the Generalized Anxiety Disorder 7-item Scale (GAD-7)
* Can speak and understand English at a sufficient level to understand the study procedures and informed consent
* Available for study duration
* Available to attend in-person intervention sessions at the community location
* Able to attend remote sessions
* Knee, hip or ankle replacement
* Intra-articular corticosteroid or hyaluronic acid knee injection within 3 months
* Knee surgery within past 6 months
* Currently receiving or received within 3-months any PT for knee OA
* Currently receiving or received within 3 months any mental health intervention (excluding pharmacologic treatments)
* Planning to initiate physical therapy for joint or low back pain in the next 3months
* Planning to initiate any mental health treatment (excluding pharmacologic treatments) in the next 1 month.
* Systemic inflammatory arthritis (e.g., rheumatoid arthritis)
* Neurologic conditions (e.g., stroke, Parkinson's disease, etc.)
* Contraindications to starting an exercise program.
* Suspected substance abuse
* Lack capacity to consent
* Pregnancy (self-report)
* Participation in another clinical trial for any joint or muscle pain
* Planning for a major surgery in the next 6 months
* Having high risk mental health symptoms (active suicidality, bipolar disorder, mania, psychosis, schizophrenia)
* Receiving chemotherapy or radiation therapy for cancer (except non-melanoma skin cancer)

Pregnancy or breastfeeding
Severe psychiatric disorders
Active substance abuse
Unstable medical conditions
Inability to comply with study requirements

Contacts and Locations

Study Contact

Deepak Kumar, PhD,PT

CONTACT

617-358-3037

kumard@bu.edu

Hosea Boakye, MPH, PT

CONTACT

6173588142

hboakye@bu.edu

Study Locations (Sites)

Boston University

Boston, Massachusetts, 02215

United States

Collaborators and Investigators

Sponsor: Boston University Charles River Campus

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-17

Study Completion Date2026-12-30

Study Record Updates

Study Start Date2025-02-17

Study Completion Date2026-12-30

Terms related to this study

Keywords Provided by Researchers

chronic pain
depression
anxiety
exercise
cognitive behavioral therapy
Black adults

Additional Relevant MeSH Terms

Osteoarthritis, Knee