RECRUITING

Effects of Multiple-Session Transcranial Direct Current Stimulation (tDCS) on Behavioral, Physiological, and Electrophysiological Measures With Adults With Autism Spectrum Disorder (ASD)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this clinical trial is to investigate the effects of multiple sessions of transcranial direct current stimulation (tDCS) delivered while participants complete tasks that target social learning with high functioning adults with ASD and/or high traits of ASD. The main question it aims to answer is: What are the effects of multiple sessions of active compared to sham tDCS, with tDCS simultaneously paired with social learning tasks, from employing a within-subject, cross-over randomized controlled trial design? Participants will: * Complete a randomly assigned block of 5 sessions of active and a block of 5 sessions of sham tDCS, with a four-week break occurring between the two blocks. * Complete social learning tasks simultaneously during receipt of tDCS at each session (whether receiving active or sham tDCS). * Complete behavioral, physiological, and electrophysiological testing before and after each block of active or sham tDCS. * Complete a social validity questionnaire after completion of the study.

Official Title

Effects of Multiple-Session Transcranial Direct Current Stimulation (tDCS) on Behavioral, Physiological, and Electrophysiological Measures With Adults With Autism Spectrum Disorder (ASD)

Quick Facts

Study Start:2025-03-04
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06495684

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 35 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Age 18-35 years
  2. 2. Proficient in English
  3. 3. Classification of autism or autism spectrum disorder on Autism Diagnostic Observation Scale, 2nd Edition (ADOS-2) or score of \>= 17 on Autism Quotient (AQ)
  4. 4. Good or corrected vision and hearing
  5. 5. Right-handed based on the Edinburgh Handedness Inventory
  6. 6. Score of \>= 85 on Shipley-2
  7. 1. No known loss of consciousness for \> 5 minutes
  8. 2. No immediate biological family members with a history of epilepsy or seizure disorder
  9. 3. No major medical needs (e.g., neurological disorders such as a seizure disorder; long-term illness)
  10. 4. No surgically implanted metal above the neck (example: metal pins or plates, cochlear implants, aneurysm clips, brain electrodes)
  11. 5. No hospitalization for depression, anxiety, or substance abuse in the past 12 months
  12. 6. No individuals who are currently pregnant
  13. 7. No pacemakers
  14. 8. No history of neurological disorders such as stroke, multiple sclerosis, bipolar disorder, encephalitis, epilepsy, seizure disorder, or amyotrophic lateral sclerosis
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Joan Esse Wilson, Ph.D.
CONTACT
575-646-4313
joanwilson@unm.edu

Principal Investigator

Bill Shuttleworth, Ph.D.
STUDY_DIRECTOR
University of New Mexico

Study Locations (Sites)

University of New Mexico
Albuquerque, New Mexico, 87131
United States

Collaborators and Investigators

Sponsor: University of New Mexico

  • Bill Shuttleworth, Ph.D., STUDY_DIRECTOR, University of New Mexico

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-04
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2025-03-04
Study Completion Date2025-06-30

Terms related to this study

Additional Relevant MeSH Terms

  • Autism Spectrum Disorder
  • Autism or Autistic Traits