Antidepressant Adherence for Depressed Adults in Primary Care

Description

The goal of this randomized controlled trial study is to compare different adherence support strategies for primary care patients with depression who have been newly prescribed antidepressant medications. We will examine whether personalized daily text messages with and without financial incentives improves anti-depressant adherence and depression symptoms as compared to treatment as usual (no messages or incentives for taking medications). We will measure adherence with a wireless pill bottle and by assessment of electronic health prescription records. Participants in the study will be asked to complete assessments of depression symptoms via telephone at 6 and 12 weeks.

Conditions

Depression

Study Overview

Study Details

Study overview

The goal of this randomized controlled trial study is to compare different adherence support strategies for primary care patients with depression who have been newly prescribed antidepressant medications. We will examine whether personalized daily text messages with and without financial incentives improves anti-depressant adherence and depression symptoms as compared to treatment as usual (no messages or incentives for taking medications). We will measure adherence with a wireless pill bottle and by assessment of electronic health prescription records. Participants in the study will be asked to complete assessments of depression symptoms via telephone at 6 and 12 weeks.

Testing Tailored Text Reminders and Financial Incentives to Enhance Antidepressant Adherence for Depressed Adults in Primary Care

Antidepressant Adherence for Depressed Adults in Primary Care

Condition
Depression
Intervention / Treatment

-

Contacts and Locations

Philadelphia

University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States, 19104

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Penn Medicine primary care outpatients
  • * Clinical diagnosis of major depressive disorder
  • * A score of 10 on the Patient Health Questionnaire 9 (PHQ-9)
  • * Age 21 to 64 years at the time of study entry
  • * Prescribed an antidepressant by their primary care clinician
  • * Express interest in taking antidepressant medication
  • * Own a cell phone
  • * Capable of using the electronic pill bottle
  • * Treated with antidepressants in the past 90 days
  • * Pregnant or post-partum
  • * An active substance use disorder other than nicotine
  • * A lifetime history of treatment for bipolar disorder or schizophrenia
  • * Hospital admission or emergency department visit for suicidal symptoms in the past year
  • * Lack capacity to provide informed consent

Ages Eligible for Study

21 Years to 64 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pennsylvania,

Study Record Dates

2029-03-31