RECRUITING

Ketamine for Methamphetamine Use Disorder

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to determine whether treatment response with IV ketamine is superior to treatment response with IV midazolam in adults with moderate to severe MUD. The study design is a 12-week randomized, double-blind, controlled trial comparing intravenous (IV) ketamine against IV midazolam, delivered over six weeks in 120 adults with moderate to severe methamphetamine use disorder (MUD).

Official Title

NIDA CTN-0132 Randomized, Double-Blind, Active Placebo-Controlled Trial of Ketamine for Methamphetamine Use Disorder (KMD)

Quick Facts

Study Start:2024-09-11
Study Completion:2027-04-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06496750

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

McKenna Dougherty
CONTACT
469-602-2362
mckenna.dougherty@utsouthwestern.edu
Manish Jha, MBBS
CONTACT
manish.jha@utsouthwestern.edu

Principal Investigator

Manish Jha, MBBS
PRINCIPAL_INVESTIGATOR
Associate Professor

Study Locations (Sites)

Interdisciplinary Substance Use and Brain Injury Facility
Albuquerque, New Mexico, 87106
United States
Addiction Institute of Mount Sinai
New York, New York, 10029
United States
Prisma Health
Greenville, South Carolina, 29617
United States
UT Southwestern Medical Center
Dallas, Texas, 75247
United States

Collaborators and Investigators

Sponsor: University of Texas Southwestern Medical Center

  • Manish Jha, MBBS, PRINCIPAL_INVESTIGATOR, Associate Professor

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-09-11
Study Completion Date2027-04-01

Study Record Updates

Study Start Date2024-09-11
Study Completion Date2027-04-01

Terms related to this study

Additional Relevant MeSH Terms

  • Substance Use Disorders
  • Substance Use
  • Methamphetamine Abuse