This study aims to determine whether treatment response with IV ketamine is superior to treatment response with IV midazolam in adults with moderate to severe MUD. The study design is a 12-week randomized, double-blind, controlled trial comparing intravenous (IV) ketamine against IV midazolam, delivered over six weeks in 120 adults with moderate to severe methamphetamine use disorder (MUD).
Substance Use Disorders, Substance Use, Methamphetamine Abuse
This study aims to determine whether treatment response with IV ketamine is superior to treatment response with IV midazolam in adults with moderate to severe MUD. The study design is a 12-week randomized, double-blind, controlled trial comparing intravenous (IV) ketamine against IV midazolam, delivered over six weeks in 120 adults with moderate to severe methamphetamine use disorder (MUD).
Ketamine for Methamphetamine Use Disorder
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Interdisciplinary Substance Use and Brain Injury Facility, Albuquerque, New Mexico, United States, 87106
Addiction Institute of Mount Sinai, New York, New York, United States, 10029
Prisma Health, Greenville, South Carolina, United States, 29617
UT Southwestern Medical Center, Dallas, Texas, United States, 75247
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to 65 Years
ALL
No
University of Texas Southwestern Medical Center,
Manish Jha, MBBS, PRINCIPAL_INVESTIGATOR, Associate Professor
2027-04-01