Eccentric Exercise and Fatigue in Multiple Sclerosis

Description

The goal of this observational study is to compare the impact of eccentric resistance training to traditional resistance training on fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: is eccentric resistance training more fatiguing than traditional resistance training in persons with MS?. Participants will be asked to come for two sessions for two weeks. In the first week, subjects will undergo a bout of either traditional or eccentric resistance training. The next day they will return to assess their level of fatigue. The following week the subject will return and undergo whatever type of training they did not experience the first week, and it's effects on fatigue will again be assessed. The difference between the subjects level of fatigue for either condition will be compared.

Conditions

Multiple Sclerosis, Fatigue

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Study Overview

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Study Details

Study overview

The goal of this observational study is to compare the impact of eccentric resistance training to traditional resistance training on fatigue in persons with multiple sclerosis (MS). The primary question this study is asking is the following: is eccentric resistance training more fatiguing than traditional resistance training in persons with MS?. Participants will be asked to come for two sessions for two weeks. In the first week, subjects will undergo a bout of either traditional or eccentric resistance training. The next day they will return to assess their level of fatigue. The following week the subject will return and undergo whatever type of training they did not experience the first week, and it's effects on fatigue will again be assessed. The difference between the subjects level of fatigue for either condition will be compared.

The Effect of Lower Extremity Eccentric Resistance Training on Fatigue in Multiple Sclerosis

Eccentric Exercise and Fatigue in Multiple Sclerosis

Condition
Multiple Sclerosis
Intervention / Treatment

-

Contacts and Locations

New York

Hunter College, Physical Therapy Department, City University of New York, New York, New York, United States, 10010

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Definitive diagnosis of Multiple Sclerosis.
  • * Ability to walk for 6 minutes continuously with or without assistive device
  • * Ability read, understand and sign and informed consent
  • * Evidence of recent exacerbation in the last 2 months prior to starting the study
  • * Orthopedic, cardiopulmonary, or non -MS neurologic condition that could interfere with carrying out the study protocol

Ages Eligible for Study

18 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Hunter College of City University of New York,

Study Record Dates

2026-12-30