A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA)

Description

The primary purpose of the study is to determine if IVT injections of ANX007 every month reduce vision loss in participants with GA secondary to age-related macular degeneration (AMD).

Conditions

Geographic Atrophy

Study Overview

Study Details

Study overview

The primary purpose of the study is to determine if IVT injections of ANX007 every month reduce vision loss in participants with GA secondary to age-related macular degeneration (AMD).

A Phase 3, Multicenter, Randomized, Parallel-Group, Double-Masked, 2-Arm, Sham Controlled Study of the Efficacy, Safety, and Tolerability of ANX007 Administered by Intravitreal Injection in Patients With Geographic Atrophy (GA) Secondary to Age Related Macular Degeneration (AMD)

A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of ANX007 in Participants With Geographic Atrophy (GA)

Condition
Geographic Atrophy
Intervention / Treatment

-

Contacts and Locations

Scottsdale

Retina Macula Institute of Arizona, Scottsdale, Arizona, United States, 85255

Beverly Hills

Retina-Vitreous Associates Medical Group, Beverly Hills, California, United States, 90211

Fullerton

RCOC Clinical Research Institute Inc, Fullerton, California, United States, 92835

Modesto

Retina Consultants Medical Group, Modesto, California, United States, 95356

Mountain View

Northern California Retina Vitreous Associates Medical Group, Inc., Mountain View, California, United States, 94040

Poway

Retina Consultants of San Diego, Poway, California, United States, 92064

Sacramento

Retinal Consultants Medical Group Inc, Sacramento, California, United States, 95825

Santa Ana

Orange County Retina Medical Group, Santa Ana, California, United States, 92705

Walnut Creek

Bay Area Retina Associates Walnut Creek, Walnut Creek, California, United States, 94598

Jacksonville

Florida Retina Institute- Jacksonville, Jacksonville, Florida, United States, 32216

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of GA of the macula secondary to AMD as determined by the Investigator and confirmed by the independent Central Reading Center.
  • * Geographic atrophy due to other causes than AMD such as Stargardt disease, cone-rod dystrophy, pathologic myopia, or toxic maculopathies (for example, plaquenil maculopathy) in either eye.

Ages Eligible for Study

50 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Annexon, Inc.,

Clinical Trials, STUDY_DIRECTOR, Annexon, Inc.

Study Record Dates

2027-10-31