HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Description

The focus of this pilot will be on falls and neurocognitive symptoms, and the impact of alcohol, cannabis use, and medications on these outcomes. The rationale is that alcohol use at any level may interact with neurocognitively active medications, alcohol, and cannabis use leading to falls and impaired cognition.

Conditions

Hiv, Alcohol Drinking, Fall, Cannabis Use

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Study Overview

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Study Details

Study overview

The focus of this pilot will be on falls and neurocognitive symptoms, and the impact of alcohol, cannabis use, and medications on these outcomes. The rationale is that alcohol use at any level may interact with neurocognitively active medications, alcohol, and cannabis use leading to falls and impaired cognition.

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Condition
Hiv
Intervention / Treatment

-

Contacts and Locations

West Haven

VA Connecticut Healthcare System, West Haven, Connecticut, United States, 06516

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * HIV+
  • * have visited a local VA site in within the past year
  • * had an AUDIT-C indicating current alcohol use
  • * taking 5 or more non-ART medications, including an NCAM (i.e., benzodiazepines, opioids, muscle relaxants, sleeping medication, and selective serotonin reuptake inhibitors)
  • * Inpatient individuals
  • * Patients with an Alcohol Use Disorder (AUD) diagnosis in the past 12 months
  • * Patients who test positive on the Alcohol Symptom Checklist for moderate or severe AUD during the screening process

Ages Eligible for Study

50 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Yale University,

Amy C Justice, MD, PhD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

2025-12