RECRUITING

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The focus of this pilot will be on falls and neurocognitive symptoms, and the impact of alcohol, cannabis use, and medications on these outcomes. The rationale is that alcohol use at any level may interact with neurocognitively active medications, alcohol, and cannabis use leading to falls and impaired cognition.

Official Title

HIV and Alcohol Research Center Focused on Polypharmacy (HARP) Pilot 2 (2nd HARP Pilot Intervention)

Quick Facts

Study Start:2025-01
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06513819

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * HIV+
  2. * have visited a local VA site in within the past year
  3. * had an AUDIT-C indicating current alcohol use
  4. * taking 5 or more non-ART medications, including an NCAM (i.e., benzodiazepines, opioids, muscle relaxants, sleeping medication, and selective serotonin reuptake inhibitors)
  1. * Inpatient individuals
  2. * Patients with an Alcohol Use Disorder (AUD) diagnosis in the past 12 months
  3. * Patients who test positive on the Alcohol Symptom Checklist for moderate or severe AUD during the screening process

Contacts and Locations

Study Contact

Amy C Justice, MD, PhD
CONTACT
203-932-5711
amy.justice2@va.gov

Principal Investigator

Amy C Justice, MD, PhD
PRINCIPAL_INVESTIGATOR
Yale University

Study Locations (Sites)

VA Connecticut Healthcare System
West Haven, Connecticut, 06516
United States

Collaborators and Investigators

Sponsor: Yale University

  • Amy C Justice, MD, PhD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01
Study Completion Date2025-12

Study Record Updates

Study Start Date2025-01
Study Completion Date2025-12

Terms related to this study

Additional Relevant MeSH Terms

  • Hiv
  • Alcohol Drinking
  • Fall
  • Cannabis Use