RECRUITING

QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

QUELIMMUNE is FDA-approved under an HDE for the treatment of pediatric patients (weight ≥10kg and age ≤22 years) with AKI due to sepsis or a septic condition on antibiotic therapy and requiring RRT. The purpose of this surveillance registry is to prospectively collect safety data among all patients treated with QUELIMMUNE under the HDE. More specifically, we intend on comparing the incidence of new (secondary) blood stream infections in the first 28 days after SCD-PED initiation to a comparator group of matched CKRT patients with sepsis who did not receive treatment with QUELIMMUNE

Official Title

Pediatric Selective Cytopheretic Device (SCD-PED, QUELIMMUNE) for Critically Ill Children with Acute Kidney Injury: a Humanitarian Device Exemption (HDE) Surveillance Registry Protocol

Quick Facts

Study Start:2024-07-19
Study Completion:2026-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06517810

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 22 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * All patients initiated on QUELIMMUNE therapy under the HDE-approved indication
  1. * Weight ≤10kg
  2. * Age \>22 years
  3. * Known allergy to any components of QUELIMMUNE

Contacts and Locations

Study Contact

Mohamed Zidan, MD
CONTACT
844-427-8100
mzidan@seastarmed.com
Kevin K Chung, MD
CONTACT
844-427-8100
kchung@seastarmed.com

Study Locations (Sites)

Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611
United States
Cincinnati Children's Hospital
Cincinnati, Ohio, 45229
United States

Collaborators and Investigators

Sponsor: SeaStar Medical

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-19
Study Completion Date2026-05

Study Record Updates

Study Start Date2024-07-19
Study Completion Date2026-05

Terms related to this study

Keywords Provided by Researchers

  • continuous kidney replacement therapy
  • continuous renal replacement therapy
  • acute kidney injury
  • organ failure
  • inflammation
  • dialysis

Additional Relevant MeSH Terms

  • Acute Kidney Injury
  • Acute Kidney Injury Due to Sepsis