RECRUITING

A Novel Imaging Modality to Evaluate Radiation-Induced Uterine Injury

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this pilot study is to assess the ability of a new imaging modality, shear-wave-elastography (SWE) and magnetic resonance imaging (MRI) to identify radiation-induced uterine injury (RIUI). The investigator will recruit female patients treated for colorectal or anal cancer at 15 to 39 years with ≥ 50 Gy pelvic radiation (PRT) at least 12 months prior to study initiation.

Official Title

A Novel Imaging Modality to Evaluate Radiation-Induced Uterine Injury

Quick Facts

Study Start:2024-06-01
Study Completion:2025-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06518174

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:15 Years to 40 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Female
  2. 2. 15 ≤ age of treatment \< 40 years
  3. 3. Treated with PRT at UCH
  4. 4. Received ≥ 50 Gy PRT
  1. 1. Patients who underwent hysterectomy for treatment of a primary gynecologic malignancy
  2. 2. Patients that are currently pregnant

Contacts and Locations

Study Contact

Leslie Appiah, MD
CONTACT
720-926-1970
LESLIE.APPIAH@CUANSCHUTZ.EDU
Jocelyn Phipers, NP
CONTACT
303-724-7807
Jocelyn.Phipers@cuanschutz.edu

Principal Investigator

Leslie Appiah, MD
PRINCIPAL_INVESTIGATOR
University of Colorado, Denver

Study Locations (Sites)

University of Colorado
Aurora, Colorado, 80045
United States
University of Colorado
Aurora, Colorado, 80045
United States

Collaborators and Investigators

Sponsor: University of Colorado, Denver

  • Leslie Appiah, MD, PRINCIPAL_INVESTIGATOR, University of Colorado, Denver

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-06-01
Study Completion Date2025-03

Study Record Updates

Study Start Date2024-06-01
Study Completion Date2025-03

Terms related to this study

Keywords Provided by Researchers

  • Uterine Injury
  • Radiation

Additional Relevant MeSH Terms

  • Uterine Injury