Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder

Description

This study aims to examine the effects of Low-Intensity Focused Ultrasound (LIFU) on brain activity in patients with alcohol use disorder.

Conditions

Alcohol Use Disorder

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Study Overview

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Study Details

Study overview

This study aims to examine the effects of Low-Intensity Focused Ultrasound (LIFU) on brain activity in patients with alcohol use disorder.

Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder

Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder

Condition
Alcohol Use Disorder
Intervention / Treatment

-

Contacts and Locations

San Francisco

University of California, San Francisco, San Francisco, California, United States, 94143

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Male or female ≥ 18 years of age.
  • 2. Documentation of an AUD diagnosis per DSM-5 criteria as evidenced by problematic pattern of alcohol use leading to clinically significant impairment or distress, as manifested by at least two of the DSM-5 criteria, occurring within a 12-month period.
  • 3. Be willing to undergo a brain MRI and follow study protocol.
  • 1. Pregnant or breastfeeding.
  • 2. Presence of a condition or abnormality that would compromise the safety of the patient or the quality of the data.
  • 3. Non-English speaking.
  • 4. Other investigational AUD treatments.
  • 5. Primary psychosis, Bipolar I, or severe personality disorder.
  • 6. Active suicidality or history of suicide attempt in the past 5 years.
  • 7. Cognitive impairment (MoCA \<24)
  • 8. Significant medical or neurological disease, or life expectancy \<12 mos.
  • 9. Significant brain abnormality on brain imaging.
  • 10. Any MRI exclusion criteria.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of California, San Francisco,

Khaled Moussawi, MD, PhD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

2027-09