COMPLETED

Cardiovascular Response to Isometric BFR Exercise

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this interventional study is to evaluate the acute impact of isometric blood flow restriction (BFR) exercise on blood pressure and other cardiovascular functions in healthy young adult volunteers. The main question it aims to answer is: The investigators hypothesize that isometric BFR exercise with a wide-rigid cuff would lead to greater blood pressure and other cardiovascular responses and that these cardiovascular responses would be greater under isometric BFR exercise with narrow-elastic bands compared with the control condition (no cuff). Participants will perform isometric exercises in 3 laboratory visits with different exercise conditions) no cuff control 2) BFR with wide-rigid cuff 3) BFR with narrow-elastic band.

Official Title

Blood Pressure Responses to Isometric Blood Flow Restriction Exercise

Quick Facts

Study Start:2024-12-02
Study Completion:2025-05-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06529068

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 40 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. * Abnormal clotting times
  2. * Acid-base imbalance/acidosis
  3. * Arterial calcification
  4. * Atherosclerotic vessels
  5. * Cardiopulmonary conditions
  6. * Diabetes
  7. * Dialysis/central venous access
  8. * General/local infection
  9. * High intracranial pressure
  10. * Hip, pelvis, or femur fracture
  11. * History of venous thromboembolism
  12. * Hypertension
  13. * Immobility for greater than 48 hours in the past month
  14. * Immobilizing cast
  15. * Implanted medical device
  16. * Lymphectomies
  17. * Obesity
  18. * Open fracture
  19. * Open or unhealed soft tissue injuries
  20. * Paralysis
  21. * Peripheral vascular disease
  22. * Pregnancy/postpartum
  23. * Prior revascularization
  24. * Renal compromise
  25. * Severe crush injuries
  26. * Sickle cell trait/anemia
  27. * Skin grafts
  28. * Stroke
  29. * Temporary nerve damage
  30. * Thrombophilia
  31. * Tumor/cancer
  32. * Varicose veins
  33. * Vascular grafting

Contacts and Locations

Study Locations (Sites)

Cardiovascular Aging Research Laboratory
Austin, Texas, 78712-1415
United States

Collaborators and Investigators

Sponsor: University of Texas at Austin

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-02
Study Completion Date2025-05-30

Study Record Updates

Study Start Date2024-12-02
Study Completion Date2025-05-30

Terms related to this study

Additional Relevant MeSH Terms

  • Blood Pressure