RECRUITING

Skin Wetting in Burn Survivors

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This project will identify the efficacy of whole body skin wetting aimed to attenuate excessive elevations in internal body temperatures during physical activity in well-healed burn survivors. The investigators will conduct a randomized crossover design study. Non-burned control subjects, subjects who experienced burns covering \~20% to 40% of their body surface area, and subject having burns \>40% of their body surface area will be investigated. Subjects will exercise in heated environmental conditions while receiving no cooling or whole body skin wetting.

Official Title

Skin Wetting in Burn Survivors

Quick Facts

Study Start:2024-07-31
Study Completion:2026-07-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06529757

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Healthy male and female subjects
  2. * 18-65 years of age.
  3. * Free of any underlying medical conditions
  4. * Any burn-related injuries resulting in at least one night of hospitalization.
  5. * Heart disease or any other chronic medical condition requiring regular medical therapy including cancer, diabetes, and hypertension.
  6. * Abnormalities detected on routine screening
  7. * Individuals who participate in a structured aerobic exercise training program at moderate to high intensities.
  8. * Current smokers, as well as individuals who regularly smoked within the past 3 years.
  9. * Body mass index of greater than 30 kg/m\^2.
  10. * Pregnant individuals
  11. * Healthy male and female subjects
  12. * 18-65 years of age.
  13. * Free of any underlying medical conditions
  14. * Having a burn injury covering 20-40% or \>40% of the participant's body surface area; at least 50% of those burn injuries must be full thickness that required skin grafting.
  15. * Participants must have been hospitalized due to the burn injury for a minimum of 15 days
  16. * Any burn-related injuries resulting in at least one night of hospitalization.
  17. * Heart disease or any other chronic medical condition requiring regular medical therapy including cancer, diabetes, and hypertension.
  18. * Abnormalities detected on routine screening
  19. * Individuals who participate in a structured aerobic exercise training program at moderate to high intensities.
  20. * Current smokers, as well as individuals who regularly smoked within the past 3 years.
  21. * Body mass index of greater than 30 kg/m\^2.
  22. * Pregnant individuals
  23. * Extensive unhealed injured skin
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Craig Crandall, PhD
CONTACT
214-345-4623
craigcrandall@texashealth.org
Taysom Wallace, MS
CONTACT
214-345-5022
taysomwallace@texashealth.org

Study Locations (Sites)

Institute for Exercise and Environmental Medicine
Dallas, Texas, 75231
United States

Collaborators and Investigators

Sponsor: University of Texas Southwestern Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-31
Study Completion Date2026-07-31

Study Record Updates

Study Start Date2024-07-31
Study Completion Date2026-07-31

Terms related to this study

Additional Relevant MeSH Terms

  • Burn Injury