Hematopoiesis in MBL and CLL Versus Healthy Age-Matched Control Subjects

Description

This study evaluates hematopoiesis to determine how MBL/CLL affected bone marrow responds to fight off infections in the body.

Conditions

Chronic Lymphocytic Leukemia, Monoclonal B-Cell Lymphocytosis

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Study Overview

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Study Details

Study overview

This study evaluates hematopoiesis to determine how MBL/CLL affected bone marrow responds to fight off infections in the body.

Hematopoiesis in Monoclonal B Cell Lymphocytosis (MBL) and B-Chronic Lymphocytic Leukemia (CLL) Versus Healthy Age-Matched Control Subjects

Hematopoiesis in MBL and CLL Versus Healthy Age-Matched Control Subjects

Condition
Chronic Lymphocytic Leukemia
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic in Rochester, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Subjects in the CLL cohort who are eligible for these studies will have a clinically established diagnosis of CLL as assessed by flow cytometry and will include subjects who
  • * Remain untreated
  • * Are currently being treated
  • * Who have already been treated
  • * Subjects in the MBL cohort will have a clinically established diagnosis of MBL
  • * Healthy age-matched control subjects
  • * Healthy younger control subjects aged \> 40 years
  • * Anyone under 40
  • * Healthy control subjects must not have a diagnosis of CLL or MBL

Ages Eligible for Study

40 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Mayo Clinic,

Neil E. Kay, M.D., PRINCIPAL_INVESTIGATOR, Mayo Clinic in Rochester

Study Record Dates

2026-11-18