COMPLETED

Respiratory Training in Friedreich's Ataxia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a prospective interventional study of patients with Friedreich's Ataxia that receive respiratory strength training for a period of 12 weeks with two research visits at the beginning and at the end of the study period. Visits include swallowing evaluation with fiberoptic endoscopic evaluation of swallowing, pulmonary function testing, surface electromyography and patient surveys.

Official Title

Impact of Respiratory Training in Swallowing and Respiratory Function in Patients With Friedreich's Ataxia

Quick Facts

Study Start:2024-08-29
Study Completion:2025-08-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06539598

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * confirmed genetic testing of Friedreich's Ataxia
  2. * have an overall DIGEST score of 1 or higher based on FEES screening
  3. * are able to perform pulmonary function testing
  1. * have been on antibiotics within 15 days prior to baseline screening.
  2. * have been prescribed systemic corticosteroids or neuromuscular blocking agents within 15 days of the baseline screening
  3. * have an allergy or contraindication to topical lidocaine or oxymetazoline
  4. * have any other concurrent medical condition which, in the opinion of the investigators, would make the subject inappropriate to participate in testing or respiratory exercise

Contacts and Locations

Principal Investigator

Carmen Leon Astudillo, MD
PRINCIPAL_INVESTIGATOR
University of Florida

Study Locations (Sites)

Clinical Research Center
Gainesville, Florida, 32610
United States

Collaborators and Investigators

Sponsor: University of Florida

  • Carmen Leon Astudillo, MD, PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-08-29
Study Completion Date2025-08-07

Study Record Updates

Study Start Date2024-08-29
Study Completion Date2025-08-07

Terms related to this study

Additional Relevant MeSH Terms

  • Friedreich Ataxia