Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With Migraine

Description

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate the effectiveness of atogepant in treating adult participants with migraine in a real-world setting. Atogepant is an approved drug for preventive treatment of migraine in adults. Approximately 1000 adult participants who are prescribed atogepant by their doctors will be enrolled in this study across the world. Participants will receive atogepant oral tablets as prescribed per standard clinical practice and will be followed for 2 years. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

Conditions

Migraine

Study Overview

Study Details

Study overview

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate the effectiveness of atogepant in treating adult participants with migraine in a real-world setting. Atogepant is an approved drug for preventive treatment of migraine in adults. Approximately 1000 adult participants who are prescribed atogepant by their doctors will be enrolled in this study across the world. Participants will receive atogepant oral tablets as prescribed per standard clinical practice and will be followed for 2 years. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

A ProspeCtive ObseRvatioNal Study of Atogepant Effectiveness in Routine Clinical Practice

Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With Migraine

Condition
Migraine
Intervention / Treatment

-

Contacts and Locations

Hoover

Neurology and Neurodiagnostics of Alabama /ID# 267614, Hoover, Alabama, United States, 35244

Aliso Viejo

Kenneth Martinez MD, A Medical Corp /ID# 267834, Aliso Viejo, California, United States, 92656

Los Angeles

Los Angeles Headache Center /ID# 267570, Los Angeles, California, United States, 90067-2001

Lake Mary

Alcanza Clinical Research, LLC /ID# 267838, Lake Mary, Florida, United States, 32746-2118

Amherst

Dent Neurologic Group, Llp /Id# 267606, Amherst, New York, United States, 14226-1723

N. New Hyde Park

Grace Forde /ID# 267596, N. New Hyde Park, New York, United States, 11042-2040

Neenah

Neuroscience Group /ID# 267571, Neenah, Wisconsin, United States, 54956-1993

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * At least 1-year history of migraine with or without aura consistent with a diagnosis according to the International Classification of Headache Disorders (ICHD)-3, 2018.
  • * Prescribed atogepant according to the relevant approved local label.
  • * For participants who initiate atogepant at the prescribing physician or treating health care provider (HCP) discretion as part of their routine clinical care, the decision to administer atogepant must be made prior to and independent of recruitment into the study.
  • * Willing and able to comply with the requirements of the study.
  • * Not on concomitant preventive medication for migraine or have been on a stable preventive medication for migraine for at least 3 months prior to enrollment in the study. If on a stable preventive medication, the prescribing physician or treating HCP and participant must confirm that there is no plan to change concomitant preventive medication during the first 12 weeks of the study.
  • * Previously exposed to atogepant as routine therapy or from clinical trials experience prior to entry.
  • * Contraindications to atogepant as per local labeling.
  • * Pregnant or planning to be pregnant or women of childbearing potential not using contraception.
  • * Enrolled in any interventional studies that may include investigational compounds for migraine, or non-AbbVie observational studies.
  • * In the opinion of the prescribing physician or treating HCP, the participant has a history or current evidence of any condition that might interfere with patient's ability to comply with the study requirements.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

AbbVie,

ABBVIE INC., STUDY_DIRECTOR, AbbVie

Study Record Dates

2029-02