Real-world Patient Reported Outcomes Among Patients Treated With Camzyos

Description

This real-world study will assess changes in health status among participants with symptomatic obstructive hypertrophic cardiomyopathy who are treated with mavacamten in the real world.

Conditions

Obstructive Hypertrophic Cardiomyopathy

Study Overview

Study Details

Study overview

This real-world study will assess changes in health status among participants with symptomatic obstructive hypertrophic cardiomyopathy who are treated with mavacamten in the real world.

Real-World Camzyos Patient Reported OutcoMes Through PAtient SurveyS in Hypertrophic CardioMyopathy (COMPASS-HCM): A Prospective Longitudinal Study

Real-world Patient Reported Outcomes Among Patients Treated With Camzyos

Condition
Obstructive Hypertrophic Cardiomyopathy
Intervention / Treatment

-

Contacts and Locations

Boston

Analysis Group Inc., Boston, Massachusetts, United States, 02199

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Participants ≥18 years of age.
  • * Participants who are prescribed mavacamten for obstructive hypertrophic cardiomyopathy
  • * Provided informed consent to participate in the study
  • * Previously or currently enrolled in clinical trials for any cardiac myosin inhibitors
  • * Treated for \>7 days with mavacamten by the day of completing the baseline survey
  • * Enrolled in any clinical trials at the time of or within the six-month period prior to the screening
  • * Had heart attack requiring coronary artery bypass grafting within the three-month period prior to the screening
  • * Had stroke or transient ischemic attack within the six-month period prior to the screening
  • * Had moderate-to-severe lung disease which impacted the ability to perform daily activities of living and ability to breathe
  • * Had major lung (thoracic) or heart (cardiac) surgery within the six-month period prior to the screening
  • * Scheduled for a major surgery for the next three months, such as joint surgeries including hip replacement, abdominal surgeries, lung surgeries, heart surgeries, eye surgeries, brain surgeries, and any other major surgeries that require general anesthesia and at least an overnight hospital stay
  • * Hospitalized requiring an overnight stay at the time of or within the two-week period prior to the screening

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Bristol-Myers Squibb,

Bristol-Myers Squibb, STUDY_DIRECTOR, Bristol-Myers Squibb

Study Record Dates

2027-06-30