RECRUITING

Median Versus Ulnar Nerve Quantitative Electromyography Neuromuscular Blockade Monitoring Comparison

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Medications used to relax the muscles are used during surgery. The amount of muscle relaxation can monitored with devices that stimulate a specific nerve and evaluate the muscle response. The response to, and recovery from, medications that relax the muscles are best described for a nerve in the arm called the ulnar nerve. The investigators believe that other nerves in the arm, such as the median nerve, could be used to monitor the amount of muscle relaxation. The purpose of this study is to compare the muscle response at two different nerve sites after giving medications to relax the muscles. This study is going to measure the depth of muscle relaxation during surgery at two different sites. The muscle response to stimulation of the ulnar nerve (located in the arm) will be compared to the muscle response to stimulation of the median nerve (also located in the arm).

Official Title

Median Versus Ulnar Nerve Quantitative Electromyography Neuromuscular Blockade Monitoring Comparison

Quick Facts

Study Start:2024-12-26
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06553131

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adults 18 - 75 years of age who are able to provide consent
  2. * Scheduled for elective surgery requiring muscle relaxation, in a supine position under general anesthesia, with an anticipated duration of at least 1.5 hours
  1. * Contraindication to rocuronium use
  2. * Comorbidities that may prolong the duration of neuromuscular blockade or alter pharmacodynamics and/or pharmacokinetics, such as:
  3. * Neuromuscular disease
  4. * Expected or known difficult airway
  5. * Rocuronium allergy
  6. * BMI \< 18.5 or \> 40
  7. * History of adhesive allergy
  8. * Upper extremity weakness, limb deformity, or absence of all or part of an upper limb
  9. * Patients undergoing surgical procedures requiring cardiopulmonary bypass

Contacts and Locations

Study Contact

Melissa D McCabe, MD, MSCR
CONTACT
909 558 4475
mmccabe@llu.edu
Michael Benggon, MD
CONTACT
909 558 4475
mbenggon@llu.edu

Principal Investigator

Michael Benggon, MD
PRINCIPAL_INVESTIGATOR
Loma Linda University

Study Locations (Sites)

Loma Linda University Troesch Medical Center
Loma Linda, California, 92354
United States

Collaborators and Investigators

Sponsor: Loma Linda University

  • Michael Benggon, MD, PRINCIPAL_INVESTIGATOR, Loma Linda University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-26
Study Completion Date2025-12

Study Record Updates

Study Start Date2024-12-26
Study Completion Date2025-12

Terms related to this study

Keywords Provided by Researchers

  • Median Nerve
  • Neuromuscular Blockade
  • Ulnar Nerve

Additional Relevant MeSH Terms

  • Neuromuscular Blockade