Treatment Optimization of Brain-injured Warfighters

Description

Prescribed sub-symptomatic adaptable exercise treatment (SAET) is a potential solution that promotes recovery needs following a TBI. SAET has been shown to benefit the mind and body in ways that decrease the severity and frequency of mild TBI (mTBI) symptoms. This study aims to validate SAET as an alternative, adaptable treatment or SMs with mTBI that focuses on reducing symptoms, improving mental health, increasing physiological functioning, and ultimately returning to duty. The objective of this study is to develop a prescribed exercise treatment program for warfighters with mTBI that can be personalized for SM's needs (i.e., medical and occupational) and is adaptable to various clinical resources (e.g., forward operating bases, rural clinics, and mTBI specialty programs). The key question raised by this study is whether SAET is more effective than a stretching control group (SCG) in reducing neurobehavioral symptoms among SMs with persistent complaints following a mTBI.

Conditions

Mild Traumatic Brain Injury

Study Overview

Study Details

Study overview

Prescribed sub-symptomatic adaptable exercise treatment (SAET) is a potential solution that promotes recovery needs following a TBI. SAET has been shown to benefit the mind and body in ways that decrease the severity and frequency of mild TBI (mTBI) symptoms. This study aims to validate SAET as an alternative, adaptable treatment or SMs with mTBI that focuses on reducing symptoms, improving mental health, increasing physiological functioning, and ultimately returning to duty. The objective of this study is to develop a prescribed exercise treatment program for warfighters with mTBI that can be personalized for SM's needs (i.e., medical and occupational) and is adaptable to various clinical resources (e.g., forward operating bases, rural clinics, and mTBI specialty programs). The key question raised by this study is whether SAET is more effective than a stretching control group (SCG) in reducing neurobehavioral symptoms among SMs with persistent complaints following a mTBI.

Treatment Optimization of Brain-injured Warfighters: A Prescribed Sub-symptomatic Exercise Treatment

Treatment Optimization of Brain-injured Warfighters

Condition
Mild Traumatic Brain Injury
Intervention / Treatment

-

Contacts and Locations

Camp Pendleton

Intrepid Spirit Center, Camp Pendleton, California, United States, 92055

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Active duty, male or female, ages 18 to 55
  • * History of at least one mTBI sustained more than 1 month ago
  • * Service members (SMs) with ongoing symptoms
  • * SMs who sustained a TBI of any severity within 1 month of enrollment
  • * History of moderate, severe, or penetrating TBI
  • * Current substance use disorder
  • * History of a neurological disease (e.g., multiple sclerosis, cerebral vascular accident, brain tumor, neurodegenerative disease, or neuro-motor disorder)
  • * An acute orthopedic injury that limits the capacity to complete study procedures

Ages Eligible for Study

18 Years to 55 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

United States Naval Medical Center, San Diego,

Jason M Bailie, Phd, PRINCIPAL_INVESTIGATOR, Traumatic Brain Injury Center of Excellence (TBICoE)

Study Record Dates

2026-09