TBI Rehabilitation and Activation in Veterans

Description

This trial will evaluate the impact of a multicomponent program (TBI Rehabilitation and Activation in Veterans; TRAIN-Vets) on improving cognitive function over an 8-month trial period in older Veterans with traumatic brain injury (TBI). Older Veterans with a history of TBI and subjective cognitive complaints will be enrolled and randomly assign to either the TRAIN-Vets intervention (consisting of aquatic-based exercise training, cognitive training, and lifestyle coaching) or the Health Education Control, where they will receive educational materials about brain health and healthy lifestyles.

Conditions

Traumatic Brain Injury

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Study Overview

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Study Details

Study overview

This trial will evaluate the impact of a multicomponent program (TBI Rehabilitation and Activation in Veterans; TRAIN-Vets) on improving cognitive function over an 8-month trial period in older Veterans with traumatic brain injury (TBI). Older Veterans with a history of TBI and subjective cognitive complaints will be enrolled and randomly assign to either the TRAIN-Vets intervention (consisting of aquatic-based exercise training, cognitive training, and lifestyle coaching) or the Health Education Control, where they will receive educational materials about brain health and healthy lifestyles.

TBI Rehabilitation and Activation in Veterans (TRAIN-Vets)

TBI Rehabilitation and Activation in Veterans

Condition
Traumatic Brain Injury
Intervention / Treatment

-

Contacts and Locations

Palo Alto

VA Palo Alto Health Care System, Palo Alto, California, United States, 94304-1207

San Francisco

San Francisco VA Health Care System, San Francisco, California, United States, 94121

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Veteran, age 50-89 years
  • * History (more than 6 months post injury) of mild or moderate TBI defined by the Ohio State University TBI Identification Method and DOD/VA Clinical Practice Guidelines for Definition of TBI
  • * Sufficient vision and hearing to allow cognitive testing
  • * Willingness to participate in water-based exercise program + cognitive training program for eight months
  • * Approval of primary medical provider to participate in a water-based exercise program
  • * Subjective cognitive complaints as evidenced by self-report
  • * English proficiency to allow for cognitive testing
  • * Internet connected device to participate in testing and cognitive training
  • * Current severe and unstable psychiatric disorder
  • * Diagnosis of dementia, Montreal Cognitive Assessment score less than 18, or delirium
  • * TBI within the past 6 months
  • * Acute illness or unstable chronic illness
  • * Current severe cardiac disease
  • * Severe TBI or open head injury
  • * Inability to exercise consistently
  • * Inability to read, verbalize understanding, and voluntarily sign the Informed Consent

Ages Eligible for Study

50 Years to 89 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Northern California Institute of Research and Education,

Kristine Yaffe, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

2028-02