Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Age 18+
- * Active SF firefighter
- * Willing to consume a plant-based diet (vegetables, fruit, whole grains, legumes, etc.)
- * Willing to complete 4 clinic visits
- * Weight \< 110 lb
- * BMI \>= 40
- * Self-reported uncontrolled hypercholesterolemia, hypertension or diabetes
- * Pregnant, lactating, or planning to become pregnant during the course of the study.
- * Use of any of the following drugs/supplements within the last 2 months:
- * systemic antibiotics, antifungals, antivirals, or antiparasitics (intravenous, intramuscular, or oral);
- * corticosteroids (intravenous, intramuscular, oral, nasal or inhaled);
- * cytokines;
- * methotrexate or immunosuppressive cytotoxic agents.
- * Chronic, clinically significant, or unstable (unresolved, requiring ongoing changes to medical management or medication) pulmonary, cardiovascular, gastrointestinal, hepatic or renal functional abnormality, as determined by medical history, Type 1 diabetes, dialysis
- * History of active cancer in the past 3 years except for squamous or basal cell carcinomas of the skin that have been medically managed by local excision
- * Unstable dietary history as defined by major changes in diet during the previous month, where the subject has eliminated or significantly increased a major food group in the diet.
- * Recent history of chronic excessive alcohol consumption defined as more than five 1.5-ounce servings of 80 proof distilled spirits, five 12-ounce servings of beer or five 5-ounce servings of wine per day; or \> 14 drinks/week.
- * Any confirmed or suspected condition/state of immunosuppression or immunodeficiency (primary or acquired) including HIV infection, multiple sclerosis, and Graves' disease.
- * Surgery of the GI tract, with the exception of cholecystectomy and appendectomy, in the past five years. Any major bowel resection at any time.
- * Regular/frequent use of smoking or chewing tobacco, e-cigarettes, cigars or other nicotine-containing products
- * Regular use of prescription opiate pain medication
Ages Eligible for Study
18 Years to
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
Yes