Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

Description

The purpose of this research is to understand cancer related fatigue in patients with non-small cell lung cancer (NSCLC), who are being treated with an immune checkpoint inhibitor.

Conditions

Non-small Cell Lung Cancer

Study Overview

Study Details

Study overview

The purpose of this research is to understand cancer related fatigue in patients with non-small cell lung cancer (NSCLC), who are being treated with an immune checkpoint inhibitor.

Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

Condition
Non-small Cell Lung Cancer
Intervention / Treatment

-

Contacts and Locations

Charlotte

Atrium Health Levine Cancer, Charlotte, North Carolina, United States, 28204

Winston-Salem

Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina, United States, 27157

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * ≥ 18 years of age at the time of study entry.
  • * Patients with inoperable NSCLC confirmed by histologic or cytologic documentation and by clinical assessment.
  • * Patients have completed at least two cycles of immune checkpoint inhibitors (adjuvant, unresectable, or advanced metastatic disease) as a monotherapy.
  • * If adjuvant or unresectable, immunotherapy must be planned for at least one year.
  • * If advanced metastatic NSCLC, immunotherapy must be planned for at least two years.
  • * Self-reported cancer or treatment related fatigue as noted in the patient's medical record or per treating physician.
  • * Life expectancy of greater than 6 months.
  • * 18 years of age at the time of study entry.
  • * A family member or friend helping a patient with NSCLC would be eligible for this study in any of the following ways as outlined by the National Cancer Institute:
  • * Helping with day-to-day activities such as doctor visits or preparing food
  • * Giving medicines or helping with physical therapy or other clinical tasks
  • * Helping with tasks of daily living such as using the bathroom or bathing
  • * Coordinating care and services from a distance by phone or email
  • * Giving emotional and spiritual support
  • * Patients who are currently receiving or have received chemotherapy and/or radiation within the past 1 year.
  • * Diagnosis of dementia.
  • * History of clinical depression.
  • * Current treatment for sarcopenia and anemia or hemoglobin below 10.
  • * Untreated hypothyroidism.
  • * Symptomatic heart failure.
  • * Oxygen dependent lung disease.
  • * Cognitively unable to complete interviews.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Wake Forest University Health Sciences,

Dori Beeler, PRINCIPAL_INVESTIGATOR, Atrium Health Levine Cancer

Study Record Dates

2025-08-30