RECRUITING

Bacterial Reduction After Supplementary Disinfection Procedures in Infected Root Canals

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Conditions

Dental Pulp Necroses

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to understand the effect that 3 different types of root canal procedures have on bacteria.

Official Title

Bacterial Reduction After Supplementary Disinfection Procedures in Infected Root Canals

Quick Facts

Study Start:2024-08-20
Study Completion:2026-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06569329

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 95 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Diagnosis of pulp necrosis with apical periodontitis (AP) confirmed by pulp tests, clinical and radiographic evidence.
  2. * Tooth with no response to cold and electric pulp testing (done at screening).
  3. * Single canalled premolars with intact pulp chamber walls.
  4. * Patient must be 18 years of age or older
  1. * Teeth with vital pulp.
  2. * Teeth with incomplete root formation (immature with apical periodontitis).
  3. * Teeth with extensive crown destruction.
  4. * Teeth with previous endodontic treatment or intervention (pulp debridement).
  5. * Teeth with acute/ chronic apical abscess.
  6. * Teeth with internal or external resorption.
  7. * Teeth with non-odontogenic facial pain.
  8. * Teeth with periodontal pockets deeper than 4 mm.
  9. * Teeth with advanced untreated periodontal disease or recent periodontal surgery.
  10. * Teeth with mobility score greater than 2.
  11. * Teeth with a fracture or visible crack.
  12. * Patients with diabetes or immune compromised conditions.
  13. * Patients who received systemic antibiotics within the last 3 months.
  14. * Patients taking corticosteroids.
  15. * Patients who are pregnant.

Contacts and Locations

Study Contact

Abhishek Parolia, PhD, MDS
CONTACT
(319) 335-7471
abhishek-parolia@uiowa.edu

Principal Investigator

Abhishek Parolia, PhD, MDS
PRINCIPAL_INVESTIGATOR
University of Iowa

Study Locations (Sites)

University of Iowa College of Dentistry and Dental Clinics
Iowa City, Iowa, 52242
United States

Collaborators and Investigators

Sponsor: Abhishek Parolia

  • Abhishek Parolia, PhD, MDS, PRINCIPAL_INVESTIGATOR, University of Iowa

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-08-20
Study Completion Date2026-08

Study Record Updates

Study Start Date2024-08-20
Study Completion Date2026-08

Terms related to this study

Additional Relevant MeSH Terms

  • Dental Pulp Necroses