Impact of Plant Diet for Diabetes Prevention

Description

The primary purpose of this study is to determine the sex-specific metabolic and molecular response, among adults with prediabetes, when moving from a Western Diet to plant-based diet.

Conditions

Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)

Talk to us

Study Overview

On this page

Study Details

Study overview

The primary purpose of this study is to determine the sex-specific metabolic and molecular response, among adults with prediabetes, when moving from a Western Diet to plant-based diet.

Assessing the Impact of a Plant-Based Diet for Diabetes Prevention: Pilot Study

Impact of Plant Diet for Diabetes Prevention

Condition
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Intervention / Treatment

-

Contacts and Locations

Lexington

University of Kentucky CCTS, Lexington, Kentucky, United States, 40536

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Body mass index greater than or equal to 27
  • * High waist circumference (women greater than or equal to 35"; men greater than or equal to 40")
  • * Prediabetes (based on fasting glucose 100-125 mg/dL, HbA1c 5.7-6.4, or 2-hr post-oral glucose tolerance test glucose screen between 140-199mg/dL)
  • * Physical activity below national guidelines
  • * Aged 30-55 (premenopausal for women)
  • * Following a Western diet
  • * Diabetes diagnosis
  • * Take medications that may affect insulin sensitivity
  • * More than 5% weight change within 6 months of screening
  • * History of bariatric surgery
  • * Report any dietary supplement, medication, or medical condition known to significantly affect weight or metabolism
  • * Take hormone replacement therapy
  • * Consume 3 or more servings of combined fruit and vegetables daily and/or 3 or more servings of whole grains daily
  • * Any food allergy more severe than grade 1 on the CoFAR Grading Scale for Systemic Allergic Reactions, Version 3.0 or allergy to lidocaine

Ages Eligible for Study

30 Years to 55 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Jean L. Fry,

Jean L Fry, PhD, PRINCIPAL_INVESTIGATOR, University of Kentucky

Study Record Dates

2027-12-31