Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

Description

This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.

Conditions

COPD

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Study Overview

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Study Details

Study overview

This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.

Physiologic Effects of Nasal High Flow on Exercise Tolerance in Chronic Obstructive Pulmonary Disease (COPD)

Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

Condition
COPD
Intervention / Treatment

-

Contacts and Locations

Miami

University of Miami, Miami, Florida, United States, 33136

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Able to consent
  • * Age 18 years or older
  • * Diagnosis of COPD
  • * Ability to ambulate without assistance
  • * Use of low-flow nasal cannula ≤ 4 L/min or no supplemental oxygen (O2) at all
  • * Pregnancy
  • * Being on bedrest
  • * Inability to consent or cooperate with the study
  • * Using of \> 4 L/min of supplemental O2 or requiring non-invasive ventilation during the daytime
  • * Hemodynamic instability (resting heart rate \> 130/minute, systolic blood pressure of ≤ 90 mmHg or ≥ 180 mmHg)
  • * Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)

Ages Eligible for Study

18 Years to 100 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Miami,

Saramaria Afanador Castiblanco, M.D., PRINCIPAL_INVESTIGATOR, University of Miami

Study Record Dates

2027-12-31