Deep TMS of Neural Circuits Associated With Stimulant Use Disorder

Eligibility Criteria

• * Transcranial magnetic stimulation (TMS) and magnetic resonance imaging (MRI) contraindications: such as a cardiac pacemaker, cochlear implant, or an implanted device (deep brain stimulation, ferromagnetic metal in the head and body, claustrophobia, pregnant or breastfeeding or other ferromagnetic device/object in the head and body within 30 cm of the treatment coil.
• * General medical condition, disease, or neurological disorder that interferes with the assessments or participation.
• * Unable to safely withdraw, at least two weeks prior to treatment, from medications that increase seizure risk.
• * Current substance abuse as determined by positive toxicology screen
• * Have a mass lesion, cerebral infarct, or other active CNS disease, including a seizure disorder.
• * A recent suicide attempt (defined as within the last 30 days) or presence of current suicidal plan or intent. Patients at risk for suicide will be required to establish a written safety plan involving their primary therapist before entering the study.
• * Severe impediment to vision, hearing and/or hand movement, as this is likely to interfere with the ability to follow study protocols.
• * Greater than mild traumatic brain injury (defined as greater than 10 minutes loss of consciousness).
• * Taking benzodiazepines or neuroleptic medications, or any medication known to alter seizure threshold.
• * Acute or unstable chronic illness.
• * Current or lifetime history of bipolar disorder or psychosis.
• * Participation in another concurrent intervention-based clinical trial.