Evaluation of Biomarkers for Predicting Macronutrient Intake

Description

The goal of this clinical trial is to establish the relationship between macronutrient food intake and the resulting blood and intersticial fluid (ISF )levels of small molecule markers, as well as, validate wearable optical readers and data fusion algorithms to accurately predict individual-specific macronutrient availability in real time. The study involves 1 screening visit of approximately 2 hours and up to 4 study days of approximately 14 hours. Subjects will be asked to arrive in the fasted state on all study days. Fasting prior to screening is not required. On the screening visit, body weight, height, and body composition by Dual-energy X-ray absorptiometry (DXA) will be measured. In addition, habitual dietary intake, physical activity level (PASE), and quality of life (SGRQ-C) will be assessed.

Conditions

Glucose Metabolism, Amino Acid Metabolism

Study Overview

Study Details

Study overview

The goal of this clinical trial is to establish the relationship between macronutrient food intake and the resulting blood and intersticial fluid (ISF )levels of small molecule markers, as well as, validate wearable optical readers and data fusion algorithms to accurately predict individual-specific macronutrient availability in real time. The study involves 1 screening visit of approximately 2 hours and up to 4 study days of approximately 14 hours. Subjects will be asked to arrive in the fasted state on all study days. Fasting prior to screening is not required. On the screening visit, body weight, height, and body composition by Dual-energy X-ray absorptiometry (DXA) will be measured. In addition, habitual dietary intake, physical activity level (PASE), and quality of life (SGRQ-C) will be assessed.

Evaluation of Biomarkers for Predicting Macronutrient Intake

Evaluation of Biomarkers for Predicting Macronutrient Intake

Condition
Glucose Metabolism
Intervention / Treatment

-

Contacts and Locations

College Station

Center for Translational Research in Aging & Longevity, College Station, Texas, United States, 77843

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    50 Years to 75 Years

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    Yes

    Collaborators and Investigators

    Texas A&M University,

    Nicolaas Deutz, MD, PhD, PRINCIPAL_INVESTIGATOR, Texas A&M University

    Michael McShane, PhD, PRINCIPAL_INVESTIGATOR, Texas A&M University

    Study Record Dates

    2026-12