RECRUITING

Lidocaine Infusion Treatment for Subarachnoid Hemorrhage Headaches

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this observational study is to evaluate intravenous lidocaine efficacy and safety in treating headache following non-traumatic subarachnoid hemorrhage. Through this prospective analysis, the investigators hope to: 1. show that intravenous lidocaine infusion causes a clinically significant reduction in pain scores in patients with moderate/severe headache pain following non-traumatic subarachnoid hemorrhage; 2. show that intravenous lidocaine infusion is safe in treating headache following non-traumatic subarachnoid hemorrhage; 3. and report vasospasm prevalence in the cohort. Participants will receive lidocaine infusion as treatment for non-traumatic subarachnoid hemorrhage headache and provide pain scores (on a numeric pain scale) every two hours the patients are awake for a maximum of seven days. Monitoring for vasospasm will occur as part of the patients regular medical care.

Official Title

Lidocaine Infusion As A Treatment Modality For Headache Following Non-Traumatic Subarachnoid Hemorrhage: A Prospective, Single-Center, Observational Cohort Study

Quick Facts

Study Start:2025-01-31
Study Completion:2028-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06582810

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients \> 18 years;
  2. * Have a favorable neurological status defined as Hunt and Hess score ≤ 3 (as it accounts for patient awareness);
  3. * Can communicate numeric pain scores;
  4. * Are diagnosed with non-traumatic subarachnoid hemorrhage
  1. * The patient is diagnosed with traumatic subarachnoid hemorrhage;
  2. * If the patient is \< 18 years of age;
  3. * If numeric pain scores could not be captured for \> 3 days of hospitalization;
  4. * If the patient had a prior aneurysm;
  5. * Chronic pain not associated with non-traumatic subarachnoid hemorrhage diagnosis;
  6. * A disability before the stroke (\> 2 on modified Rankin Scale score);
  7. * A Hunt and Hess score \> 3;
  8. * Contraindications to lidocaine (significant cardiac disease, arrhythmia, seizures, previous allergic reaction to lidocaine

Contacts and Locations

Study Contact

William L Krogman, MS
CONTACT
316-268-6156
wkrogman@kumc.edu

Principal Investigator

Fernando Salgado, MD
PRINCIPAL_INVESTIGATOR
University of Kansas Medical Center

Study Locations (Sites)

Ascension Via Christi St. Francis
Wichita, Kansas, 67214
United States

Collaborators and Investigators

Sponsor: University of Kansas Medical Center

  • Fernando Salgado, MD, PRINCIPAL_INVESTIGATOR, University of Kansas Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-31
Study Completion Date2028-07

Study Record Updates

Study Start Date2025-01-31
Study Completion Date2028-07

Terms related to this study

Keywords Provided by Researchers

  • Nontraumatic Subarachnoid Hemorrhage
  • Headache
  • Lidocaine Infusion

Additional Relevant MeSH Terms

  • Subarachnoid; Hemorrhage, Nontraumatic
  • Headache