RECRUITING

The Collaborative Care PrTNER Study

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A randomized controlled trial to assess the ability of a Collaborative Care Prevention, Treatment, Navigation, Engagement, Resource (PrTNER) intervention to increase initiation of preexposure prophylaxis (PrEP) (for those at-risk for HIV) and decrease viral load (for those living with HIV) among young Black and Latino men who have sex with men (YBLMSM) aged 15 to 24 through engagement in SU treatment.

Official Title

The Collaborative Care PrTNER (Prevention, Treatment, Navigation, Engagement, Resource) Project

Quick Facts

Study Start:2025-01-02

Study Completion:2028-06

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06585631

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:15 Years to 24 Years

Sexes Eligible for Study:MALE

Accepts Healthy Volunteers:Yes

Standard Ages:CHILD, ADULT

Inclusion Criteria	Exclusion Criteria
* 15-24 years old; * Cisgender male; * Self-identified Black/African American race or Latino/Hispanic ethnicity; * Report prior oral/anal sex with another male; * At-risk for HIV (condomless anal sex or positive sexually transmitted infection (STI) in last 6 months); * A period of time in the last 6 months not taking oral PrEP/injectable PrEP exactly as prescribed; * Moderate-to-high risk SU behaviors based upon a Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT) score ≥2, * Living in Philadelphia, PA or Baltimore, MD, and surrounding areas; * Able to read and write in English * 15-24 years old; * Cisgender male; * Self-identified Black/African American race or Latino/Hispanic ethnicity; * Report prior oral/anal sex with another male; * Living with a diagnosis of HIV; * A period of time in the last 6 months not taking oral/injectable ART exactly as prescribed; * CRAFFT score ≥2, * Living in Philadelphia, PA or Baltimore, MD, and surrounding areas; * Able to read and write in English	* Participants will be excluded if they are: * Assigned female sex at birth * Identify as transgender * Outside the age criteria (\<15 or \>24 years old) * Cognitively unable to complete study requirements * Living outside of the two geographic areas * Do not screen positive for SU * No prior substance use history * No prior oral or anal sex; * Consistent oral/injectable PrEP use the last 6 months * Consistent oral/injectable ART use the last 6 months * Unable to read or write in English, * Plan to move in the next 12 months.

Inclusion Criteria

Exclusion Criteria

* 15-24 years old;
* Cisgender male;
* Self-identified Black/African American race or Latino/Hispanic ethnicity;
* Report prior oral/anal sex with another male;
* At-risk for HIV (condomless anal sex or positive sexually transmitted infection (STI) in last 6 months);
* A period of time in the last 6 months not taking oral PrEP/injectable PrEP exactly as prescribed;
* Moderate-to-high risk SU behaviors based upon a Car, Relax, Alone, Forget, Friends, Trouble (CRAFFT) score ≥2,
* Living in Philadelphia, PA or Baltimore, MD, and surrounding areas;
* Able to read and write in English
* 15-24 years old;
* Cisgender male;
* Self-identified Black/African American race or Latino/Hispanic ethnicity;
* Report prior oral/anal sex with another male;
* Living with a diagnosis of HIV;
* A period of time in the last 6 months not taking oral/injectable ART exactly as prescribed;
* CRAFFT score ≥2,
* Living in Philadelphia, PA or Baltimore, MD, and surrounding areas;
* Able to read and write in English

* Participants will be excluded if they are:
* Assigned female sex at birth
* Identify as transgender
* Outside the age criteria (\<15 or \>24 years old)
* Cognitively unable to complete study requirements
* Living outside of the two geographic areas
* Do not screen positive for SU
* No prior substance use history
* No prior oral or anal sex;
* Consistent oral/injectable PrEP use the last 6 months
* Consistent oral/injectable ART use the last 6 months
* Unable to read or write in English,
* Plan to move in the next 12 months.

Contacts and Locations

Study Contact

Renata Sanders, MD

CONTACT

215-590-5633

sandersr2@chop.edu

Principal Investigator

Renata Sanders, MD

PRINCIPAL_INVESTIGATOR

Children's Hospital of Philadelphia

Study Locations (Sites)

Johns Hopkins Center for Adolescent and Young Adult Health

Baltimore, Maryland, 21205

United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19146

United States

Collaborators and Investigators

Sponsor: Children's Hospital of Philadelphia

Renata Sanders, MD, PRINCIPAL_INVESTIGATOR, Children's Hospital of Philadelphia

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-02

Study Completion Date2028-06

Study Record Updates