Chlorhexidine Lavage for Recurrent Urinary Tract Infection

Description

A two-arm randomized control trial evaluating rates of urinary tract infection in post-menopausal women on vaginal estrogen with recurrent urinary tract infections.

Conditions

Urinary Tract Infections, Recurrent Urinary Tract Infection

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Study Overview

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Study Details

Study overview

A two-arm randomized control trial evaluating rates of urinary tract infection in post-menopausal women on vaginal estrogen with recurrent urinary tract infections.

Effect of Chlorhexidine Perineal Lavage Following Defecation in Post-Menopausal Women with Recurrent Urinary Tract Infection

Chlorhexidine Lavage for Recurrent Urinary Tract Infection

Condition
Urinary Tract Infections
Intervention / Treatment

-

Contacts and Locations

Portland

Oregon Health & Science University, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Post-menopausal female between age 55 and 89
  • * No post-menopausal bleeding
  • * Diagnosis of recurrent urinary tract infection (UTI) in the electronic health record or as two culture proven UTIs in 6 months or three culture proven UTIs in 12 months
  • * At least one UTI in the 6 months prior to entering the study
  • * Asymptomatic for UTI symptoms at the time of enrollment.
  • * On vaginal estrogen therapy for at least 6 weeks prior to enrollment
  • * Ready access to email and internet
  • * Recent prophylactic antibiotic use (washout period of 4 weeks)
  • * Neurogenic bladder
  • * Diagnosis of urinary retention
  • * Uncorrected Stage III-IV prolapse
  • * Indwelling catheter or need for intermittent self-catheterization
  • * History of complicated UTIs
  • * History of interstitial cystitis or bladder pain syndrome
  • * History of fecal incontinence/accidental bowel leakage
  • * Greater than 14 bowel movements per week
  • * Non-English speaking
  • * Allergy to chlorhexidine gluconate
  • * Inability to utilize vaginal estrogen therapy
  • * Recent urogynecological or urologic surgery (\<12 weeks)

Ages Eligible for Study

55 Years to 89 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Oregon Health and Science University,

Study Record Dates

2026-06