RECRUITING

Chlorhexidine Lavage for Recurrent Urinary Tract Infection

Conditions

Urinary Tract Infections Recurrent Urinary Tract Infection Menopause

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A two-arm randomized control trial evaluating rates of urinary tract infection in post-menopausal women on vaginal estrogen with recurrent urinary tract infections.

Official Title

Effect of Chlorhexidine Perineal Lavage Following Defecation in Post-Menopausal Women with Recurrent Urinary Tract Infection

Quick Facts

Study Start:2024-12-23

Study Completion:2026-06

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06598514

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:55 Years to 89 Years

Sexes Eligible for Study:FEMALE

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Post-menopausal female between age 55 and 89 * No post-menopausal bleeding * Diagnosis of recurrent urinary tract infection (UTI) in the electronic health record or as two culture proven UTIs in 6 months or three culture proven UTIs in 12 months * At least one UTI in the 6 months prior to entering the study * Asymptomatic for UTI symptoms at the time of enrollment. * On vaginal estrogen therapy for at least 6 weeks prior to enrollment * Ready access to email and internet	* Recent prophylactic antibiotic use (washout period of 4 weeks) * Neurogenic bladder * Diagnosis of urinary retention * Uncorrected Stage III-IV prolapse * Indwelling catheter or need for intermittent self-catheterization * History of complicated UTIs * History of interstitial cystitis or bladder pain syndrome * History of fecal incontinence/accidental bowel leakage * Greater than 14 bowel movements per week * Non-English speaking * Allergy to chlorhexidine gluconate * Inability to utilize vaginal estrogen therapy * Recent urogynecological or urologic surgery (\<12 weeks)

Inclusion Criteria

Exclusion Criteria

* Post-menopausal female between age 55 and 89
* No post-menopausal bleeding
* Diagnosis of recurrent urinary tract infection (UTI) in the electronic health record or as two culture proven UTIs in 6 months or three culture proven UTIs in 12 months
* At least one UTI in the 6 months prior to entering the study
* Asymptomatic for UTI symptoms at the time of enrollment.
* On vaginal estrogen therapy for at least 6 weeks prior to enrollment
* Ready access to email and internet

* Recent prophylactic antibiotic use (washout period of 4 weeks)
* Neurogenic bladder
* Diagnosis of urinary retention
* Uncorrected Stage III-IV prolapse
* Indwelling catheter or need for intermittent self-catheterization
* History of complicated UTIs
* History of interstitial cystitis or bladder pain syndrome
* History of fecal incontinence/accidental bowel leakage
* Greater than 14 bowel movements per week
* Non-English speaking
* Allergy to chlorhexidine gluconate
* Inability to utilize vaginal estrogen therapy
* Recent urogynecological or urologic surgery (\<12 weeks)

Contacts and Locations

Study Contact

Women's Health Research Unit Department of Ob/Gyn

CONTACT

503-494-3666

whru@ohsu.edu

Study Locations (Sites)

Oregon Health & Science University

Portland, Oregon, 97239

United States

Collaborators and Investigators

Sponsor: Oregon Health and Science University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-23

Study Completion Date2026-06

Study Record Updates

Study Start Date2024-12-23

Study Completion Date2026-06

Terms related to this study

Keywords Provided by Researchers

Menopause

Additional Relevant MeSH Terms

Urinary Tract Infections
Recurrent Urinary Tract Infection