RECRUITING

Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The overall objective is to identify the cognitive circuits associated with military aviator performance by analyzing what anatomic regions of the brain are functionally "active" (neuronal circuit) while being performing virtual flight simulations, the Precision Instrument Control Task (PICT). The flight simulation test will be conducted at two separate timepoints while the subject is receiving a Functional Magnetic Resonance Imaging (fMRI) scan to evaluate which anatomic and functional brain function is associated with precise performance. By scanning at multiple time points we aim to quantify changes in functional and anatomic connectivity that occur throughout the course of training.

Official Title

Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training

Quick Facts

Study Start:2023-09-19
Study Completion:2026-09-18
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06606925

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 54 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Active Duty Military Pilots (Instructor Pilot Trainees or Remote Piloted Aircraft Trainees)
  2. * Age 18-54 years
  3. * Biological male or female
  1. * Age \< 18 years
  2. * Age \> 60 years
  3. * Non-active-duty members
  4. * History of recurrent migraine headaches requiring chronic suppressive medication or prescription drug intervention more frequently than once per year.
  5. * History of head trauma or traumatic brain injury with any loss of consciousness or with confusion or amnesia of greater than five minutes.
  6. * History of eye trauma related to a metallic object unless the presence of residual metal has been previously excluded by x-ray.
  7. * Pregnancy
  8. * History of significant neurological disease including cerebrovascular disease, demyelinating disease, or infections of the central nervous system (encephalitis, meningitis).
  9. * History of medical conditions with potential neurological involvement such as obstructive sleep apnea, autoimmune disorders, etc.
  10. * History of seizures since age six.
  11. * Claustrophobia or intolerance of the MRI without medication.
  12. * Any medical contraindication to MRI (ex: foreign bodies, non-MRI compatible pacemaker, metal devices).

Contacts and Locations

Study Contact

Katherine Walker-Rodriguez, Program Manager, MSN
CONTACT
(210) 841-7258
katherine.c.walker-rodriguez.ctr@health.mil
Ayla Ulfberht, Research Coordinator
CONTACT
ayla.f.ulfberht.ctr@health.mil

Principal Investigator

Paul Sherman, MD
PRINCIPAL_INVESTIGATOR
59th Medical Wing Science and Technology

Study Locations (Sites)

Joint Base San Antonio - Randolph &amp; Lackland
San Antonio, Texas, 78150
United States

Collaborators and Investigators

Sponsor: The Geneva Foundation

  • Paul Sherman, MD, PRINCIPAL_INVESTIGATOR, 59th Medical Wing Science and Technology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-09-19
Study Completion Date2026-09-18

Study Record Updates

Study Start Date2023-09-19
Study Completion Date2026-09-18

Terms related to this study

Keywords Provided by Researchers

  • Pilots
  • Flight Simulator
  • fMRI
  • Training
  • Cognitive Performance
  • Neuroergonomics
  • Military

Additional Relevant MeSH Terms

  • Cognitive Performance