RECRUITING

Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Cognitive impairments are common in multiple sclerosis (MS) diagnosed both at the onset and throughout the disease course. Poor cognitive abilities have been associated with poor outcomes such as higher levels of unemployment, poor quality of life, driving difficulties among others. Learning and memory are a common cognitive deficit. This computer-based cognitive training is a 10-session treatment proven to be effective in ameliorating learning and memory in individuals with MS across 3 realms of functioning: objective cognitive performance, daily life activities and neuroimaging. Despite this strong efficacy, as well as the recent clinical application of this computer-based cognitive training across the world, recent in-person studies have highlighted that transportation to the clinic to complete treatment sessions is a significant obstacle to clinical use of this effective treatment. To address this limitation, the proposed pilot study will test the efficacy of the computer-based cognitive training administered remotely via zoom health in persons with multiple sclerosis.

Official Title

Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community

Quick Facts

Study Start:2024-09-30
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06608797

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:19 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * English as primary language
  2. * Diagnosis of multiple sclerosis
  1. * Most recent exacerbation within one month
  2. * Other Neurological History: head injury, stroke, seizures, or any other significant neurological history will not be included in the study
  3. * Individuals with an active diagnosis of Major Depressive Disorder, Schizophrenia, Bipolar Disorder I or II will be excluded from the study.
  4. * Poor Visual Acuity (corrected vision in worse eye \< 20/60), diplopia, or nystagmus
  5. * Inability to understand directions and following one, two, and three step commands
  6. * Intact New Learning and Memory: Only individuals that show impaired performance on a memory test will be included in the study

Contacts and Locations

Study Contact

Silvana L Costa Research Scientist, PhD
CONTACT
973 324 8458
scosta@kesslerfoundation.org

Study Locations (Sites)

Kessler Foundation
East Hanover, New Jersey, 07936
United States

Collaborators and Investigators

Sponsor: Kessler Foundation

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-09-30
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2024-09-30
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • learning, memory, cognitive training

Additional Relevant MeSH Terms

  • Multiple Sclerosis