RECRUITING

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The study aims to investigate whether behavioral interventions promote cessation in adult smokers by ameliorating negative emotions and improving self-control and identify the neural markers of these effects.

Official Title

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Quick Facts

Study Start:2025-04-21
Study Completion:2029-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06609369

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * English literate
  2. * report heavy tobacco use (including nicotine e-cigarettes) for \>1 year
  3. * meet biochemical cut off for recent cigarette smoking or e-cigarette use
  4. * optimal body mass index
  1. * currently enrolled in other treatments
  2. * neuropsychiatric exclusions that could interfere with study participation, increase risk of adverse events, and/or induce deficient sleep
  3. * medical contraindications for fMRI, varenicline, and/or behavioral treatment
  4. * factors that cause deficient sleep and for which behavioral treatment has less benefit
  5. * women who are pregnant or nursing

Contacts and Locations

Study Contact

Yu Chen, PhD
CONTACT
347-819-2969
yu.chen.yc838@yale.edu
Lisa Fucito, PhD
CONTACT
203-200-1470
lisa.fucito@yale.edu

Principal Investigator

Chiang-Shan Li
PRINCIPAL_INVESTIGATOR
Yale University
Lisa Fucito, PhD
PRINCIPAL_INVESTIGATOR
Yale University

Study Locations (Sites)

Connecticut Mental Health Center
New Haven, Connecticut, 06519
United States
Yale University
New Haven, Connecticut, 06520
United States

Collaborators and Investigators

Sponsor: Yale University

  • Chiang-Shan Li, PRINCIPAL_INVESTIGATOR, Yale University
  • Lisa Fucito, PhD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-04-21
Study Completion Date2029-06

Study Record Updates

Study Start Date2025-04-21
Study Completion Date2029-06

Terms related to this study

Additional Relevant MeSH Terms

  • Tobacco Use
  • Tobacco Cessation
  • Insomnia