Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Description

The study aims to investigate whether behavioral interventions promote cessation in adult smokers by ameliorating negative emotions and improving self-control and identify the neural markers of these effects.

Conditions

Tobacco Use, Tobacco Cessation, Insomnia

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Study Overview

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Study Details

Study overview

The study aims to investigate whether behavioral interventions promote cessation in adult smokers by ameliorating negative emotions and improving self-control and identify the neural markers of these effects.

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Neural Mechanisms Connecting Deficient Sleep and Smoking Relapse

Condition
Tobacco Use
Intervention / Treatment

-

Contacts and Locations

New Haven

Connecticut Mental Health Center, New Haven, Connecticut, United States, 06519

New Haven

Yale University, New Haven, Connecticut, United States, 06520

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * English literate
  • * report heavy tobacco use (including nicotine e-cigarettes) for \>1 year
  • * meet biochemical cut off for recent cigarette smoking or e-cigarette use
  • * optimal body mass index
  • * currently enrolled in other treatments
  • * neuropsychiatric exclusions that could interfere with study participation, increase risk of adverse events, and/or induce deficient sleep
  • * medical contraindications for fMRI, varenicline, and/or behavioral treatment
  • * factors that cause deficient sleep and for which behavioral treatment has less benefit
  • * women who are pregnant or nursing

Ages Eligible for Study

18 Years to 50 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Yale University,

Chiang-Shan Li, PRINCIPAL_INVESTIGATOR, Yale University

Lisa Fucito, PhD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

2029-06