RECRUITING

Acute Vitamin D Supplementation on Testosterone in Females

Conditions

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Participation will take place over two visits to the Clinical Exercise Research Center (CERC) at the University of Southern California Health Sciences Campus. On the first visit, height, weight, and body composition by bioelectrical impedance are recorded. Questionnaires and withdrawal of a sample of blood (1 tablespoon) are also completed. The intervention begins the day following the first visit. The intervention protocol consists of three weeks of consuming either a placebo capsule or a 5000 IU Vitamin D capsule daily and completing a daily survey. The second visit to CERC immediately follows the 3-weeks intervention. In this visit, the same blood sampling protocol will be completed. The assignment of the intervention will be randomized (i.e., rolling a die), and participants are blinded to group assignment.

Official Title

Effects of Acute Vitamin D Supplementation on Testosterone in Young, Healthy Females: A Pilot Study

Quick Facts

Study Start:2025-07-01

Study Completion:2026-01-30

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06610968

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 35 Years

Sexes Eligible for Study:FEMALE

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT

Inclusion Criteria	Exclusion Criteria
* Assigned female at birth * 18 to 35 years of age * No chronic diseases affecting the uptake of Vitamin D or causing Vitamin D sensitivity (e.g., sarcoidosis, tuberculosis, Wegener's granulomatosis, other forms of vasculitis, inflammatory bowel diseases, etc.) \[21\] * Completion and signature of the informed consent document * Non-pregnant or trying to become pregnant * No supplementation with Vitamin D within three months of enrollment * No documented gynecological disease (e.g., PCOS, endometriosis, etc.) * Weight greater than or equal to 110 lbs	* Pregnant * Supplementation with Vitamin D within three months of enrollment * Taking exogenous hormones * Documented gynecological disease (e.g., PCOS, endometriosis, etc.) * Suffering from chronic diseases affecting the uptake of Vitamin D or causing Vitamin D sensitivity (e.g., sarcoidosis, tuberculosis, Wegener's granulomatosis, other forms of vasculitis, inflammatory bowel diseases, etc.) \[21\] * Weight less than 110 lbs

Inclusion Criteria

Exclusion Criteria

* Assigned female at birth
* 18 to 35 years of age
* No chronic diseases affecting the uptake of Vitamin D or causing Vitamin D sensitivity (e.g., sarcoidosis, tuberculosis, Wegener's granulomatosis, other forms of vasculitis, inflammatory bowel diseases, etc.) \[21\]
* Completion and signature of the informed consent document
* Non-pregnant or trying to become pregnant
* No supplementation with Vitamin D within three months of enrollment
* No documented gynecological disease (e.g., PCOS, endometriosis, etc.)
* Weight greater than or equal to 110 lbs

* Pregnant
* Supplementation with Vitamin D within three months of enrollment
* Taking exogenous hormones
* Documented gynecological disease (e.g., PCOS, endometriosis, etc.)
* Suffering from chronic diseases affecting the uptake of Vitamin D or causing Vitamin D sensitivity (e.g., sarcoidosis, tuberculosis, Wegener's granulomatosis, other forms of vasculitis, inflammatory bowel diseases, etc.) \[21\]
* Weight less than 110 lbs

Contacts and Locations

Study Contact

Giuliet L Kibler

CONTACT

3145663995

gkibler@usc.edu

Bailey McLagan, MS

CONTACT

mclagan@usc.edu

Principal Investigator

Giuliet L Kibler

PRINCIPAL_INVESTIGATOR

University of Southern California - Division of Biokinesiology and Physical Therapy

Study Locations (Sites)

University of Southern California Health Sciences Campus Center for Health Professions

Los Angeles, California, 90033

United States

Collaborators and Investigators

Sponsor: University of Southern California

Giuliet L Kibler, PRINCIPAL_INVESTIGATOR, University of Southern California - Division of Biokinesiology and Physical Therapy

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-01

Study Completion Date2026-01-30

Study Record Updates

Study Start Date2025-07-01

Study Completion Date2026-01-30

Terms related to this study

Additional Relevant MeSH Terms

Female Hormone Profile