RECRUITING

Acute Vitamin D Supplementation on Testosterone in Females

Description

Participation will take place over two visits to the Clinical Exercise Research Center (CERC) at the University of Southern California Health Sciences Campus. On the first visit, height, weight, and body composition by bioelectrical impedance are recorded. Questionnaires and withdrawal of a sample of blood (1 tablespoon) are also completed. The intervention begins the day following the first visit. The intervention protocol consists of three weeks of consuming either a placebo capsule or a 5000 IU Vitamin D capsule daily and completing a daily survey. The second visit to CERC immediately follows the 3-weeks intervention. In this visit, the same blood sampling protocol will be completed. The assignment of the intervention will be randomized (i.e., rolling a die), and participants are blinded to group assignment.

Conditions

Female Hormone Profile
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Female Hormone Profile

Study Overview

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Study Details

Study overview

Participation will take place over two visits to the Clinical Exercise Research Center (CERC) at the University of Southern California Health Sciences Campus. On the first visit, height, weight, and body composition by bioelectrical impedance are recorded. Questionnaires and withdrawal of a sample of blood (1 tablespoon) are also completed. The intervention begins the day following the first visit. The intervention protocol consists of three weeks of consuming either a placebo capsule or a 5000 IU Vitamin D capsule daily and completing a daily survey. The second visit to CERC immediately follows the 3-weeks intervention. In this visit, the same blood sampling protocol will be completed. The assignment of the intervention will be randomized (i.e., rolling a die), and participants are blinded to group assignment.

Effects of Acute Vitamin D Supplementation on Testosterone in Young, Healthy Females: A Pilot Study

Acute Vitamin D Supplementation on Testosterone in Females

Condition
Female Hormone Profile
Intervention / Treatment

-

Contacts and Locations

Los Angeles

University of Southern California Health Sciences Campus Center for Health Professions, Los Angeles, California, United States, 90033

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Assigned female at birth
  • * 18 to 35 years of age
  • * No chronic diseases affecting the uptake of Vitamin D or causing Vitamin D sensitivity (e.g., sarcoidosis, tuberculosis, Wegener's granulomatosis, other forms of vasculitis, inflammatory bowel diseases, etc.) \[21\]
  • * Completion and signature of the informed consent document
  • * Non-pregnant or trying to become pregnant
  • * No supplementation with Vitamin D within three months of enrollment
  • * No documented gynecological disease (e.g., PCOS, endometriosis, etc.)
  • * Weight greater than or equal to 110 lbs
  • * Pregnant
  • * Supplementation with Vitamin D within three months of enrollment
  • * Taking exogenous hormones
  • * Documented gynecological disease (e.g., PCOS, endometriosis, etc.)
  • * Suffering from chronic diseases affecting the uptake of Vitamin D or causing Vitamin D sensitivity (e.g., sarcoidosis, tuberculosis, Wegener's granulomatosis, other forms of vasculitis, inflammatory bowel diseases, etc.) \[21\]
  • * Weight less than 110 lbs

Ages Eligible for Study

18 Years to 35 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Southern California,

Giuliet L Kibler, PRINCIPAL_INVESTIGATOR, University of Southern California - Division of Biokinesiology and Physical Therapy

Study Record Dates

2026-01-30