Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog

Description

This study aims to assess the effects of both acute and chronic exposures to hypoxia and hypercapnia in patients with Long COVID syndrome.

Conditions

Long COVID

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Study Overview

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Study Details

Study overview

This study aims to assess the effects of both acute and chronic exposures to hypoxia and hypercapnia in patients with Long COVID syndrome.

Pilot Study to Investigate Possible Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog

Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog

Condition
Long COVID
Intervention / Treatment

-

Contacts and Locations

Scottsdale

Mayo Clinic in Arizona, Scottsdale, Arizona, United States, 85259

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * English speaking
  • * Diagnosis of Long COVID
  • * Any history of:
  • * Coronary artery dissection or aortic dissection
  • * Neurological disease (e.g. dementia, Alzheimer's disease, or other brain-related disease)
  • * Cerebrovascular disease or stroke
  • * Aneurysm
  • * If currently has:
  • * Moderate-severe chronic obstructive pulmonary disease
  • * Uncontrolled moderate-severe asthma
  • * Moderate-severe bronchiectasis
  • * Moderate-severe interstitial lung disease, requiring the use of supplemental oxygen
  • * A necessity to use supplemental oxygen, for any reason
  • * New or worsening symptoms (decompensation) of heart failure
  • * Right heart disease due to chronic pulmonary disease/sleep apnea
  • * Uncontrolled myocardial ischemia or angina
  • * Uncontrolled heart arrhythmias
  • * Heart or lung infection (e.g. myocarditis or pericarditis)
  • * Left main coronary artery stenosis
  • * Moderate-severe aortic stenosis
  • * Pulmonary embolism, pulmonary infarction, or other blood clots
  • * Severe respiratory disease
  • * Chronic kidney disease
  • * Chronic liver disease
  • * Females of childbearing potential will complete a urine pregnancy test at their baseline visit to rule out pregnancy
  • * BMI \>40
  • * Study staff unable to obtain adequate signal for cerebral blood flow

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Courtney Wheatley-Guy, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2025-12