How Does the Type of Waveform Affect Tolerability With Transcutaneous Auricular Vagus Nerve Stimulation?

Description

The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS). The research team is interested in how the different forms affect comfort and tolerability, as well as how well it works.

Conditions

Healthy

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Study Overview

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Study Details

Study overview

The purpose of this research study is to investigate the effects of different forms of a gentle form of electrical stimulation applied to the ear, known as transcutaneous auricular vagus nerve stimulation (taVNS). The research team is interested in how the different forms affect comfort and tolerability, as well as how well it works.

How Does the Type of Waveform Affect Tolerability With Transcutaneous Auricular Vagus Nerve Stimulation?

How Does the Type of Waveform Affect Tolerability With Transcutaneous Auricular Vagus Nerve Stimulation?

Condition
Healthy
Intervention / Treatment

-

Contacts and Locations

Coral Gables

University of Miami, Plumer Building, Coral Gables, Florida, United States, 33146

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. between the ages of 18-80 years
  • 2. English speaking (must be able to consent and complete the interviews in English)
  • 1. chronic pain (average intensity \>2/10 on 0-10 scale, for longer than 3 months)
  • 2. acute pain of intensity greater than 3/10
  • 3. chronic inflammatory conditions that are poorly controlled (e.g., diabetes, autoimmune disease)
  • 4. any unstable medical condition or medical contraindication to moderate physical exertion (e.g., unstable angina or cardiac arrythmia)
  • 5. pregnancy
  • 6. currently taking Buprenorphine or recently stopped taking (within 1 month)
  • 7. presence of cognitive impairment or language barrier that impairs full autonomy in the consent process or in the ability to participate in detailed interviews
  • 8. implants in the head or neck, cochlear implants, or pacemaker
  • 9. head or neck metastasis or recent ear trauma
  • 10. history of epilepsy
  • 11. history of autonomic nervous system dysfunction (e.g., postural orthostatic tachycardia syndrome).

Ages Eligible for Study

18 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Miami,

Marlon Wong, PT, PhD, PRINCIPAL_INVESTIGATOR, University of Miami

Study Record Dates

2025-06-01