A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-refractory Multiple Myeloma (QUINTESSENTIAL-2)

Description

The purpose of this study is to compare the efficacy and safety of BMS-986393 versus standard regimens in adult participants with Relapsed or Refractory and Lanalidomide-refractory Multiple Myeloma.

Conditions

Relapsed or Refractory Multiple Myeloma (RRMM)

Study Overview

Study Details

Study overview

The purpose of this study is to compare the efficacy and safety of BMS-986393 versus standard regimens in adult participants with Relapsed or Refractory and Lanalidomide-refractory Multiple Myeloma.

A Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of BMS-986393, a GPRC5D-directed CAR-T Cell Therapy, Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-refractory Multiple Myeloma

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-refractory Multiple Myeloma (QUINTESSENTIAL-2)

Condition
Relapsed or Refractory Multiple Myeloma (RRMM)
Intervention / Treatment

-

Contacts and Locations

Birmingham

Local Institution - 0071, Birmingham, Alabama, United States, 35205

Los Angeles

UCLA Hematology/Oncology - Santa Monica, Los Angeles, California, United States, 90404

Miami

Local Institution - 0130, Miami, Florida, United States, 33136

Atlanta

Local Institution - 0058, Atlanta, Georgia, United States, 30322

Baltimore

Local Institution - 0133, Baltimore, Maryland, United States, 21218

Durham

Local Institution - 0131, Durham, North Carolina, United States, 27710

Philadelphia

Local Institution - 0097, Philadelphia, Pennsylvania, United States, 19111

Salt Lake City

Local Institution - 0044, Salt Lake City, Utah, United States, 84112

Madison

Local Institution - 0068, Madison, Wisconsin, United States, 53792

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Juno Therapeutics, Inc., a Bristol-Myers Squibb Company,

    Bristol-Myers Squibb, STUDY_DIRECTOR, Bristol-Myers Squibb

    Study Record Dates

    2032-07-21