RECRUITING

Prevent Cardiac Surgery Associated AKI Trial

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Prevent CSA-AKI (Cardiac Surgery Associated Acute Kidney Injury) trial is a double blinded randomized controlled trial, 242 patients undergoing elective cardiopulmonary bypass surgery (CPB)will either receive a placebo or daily 1200 mg of Co enzyme Q10 (CoQ10) and 1000 mg of Glutathione (GSH), the first dose will be given the day before surgery and continues while admitted up to 1 week. Blood and urine samples will be collected. Adverse events related to the study drugs will be collected.

Official Title

Efficacy of Mitochondrial Directed Therapy in Prevention of Cardiac Surgery Associated AKI Prevent Cardiac Surgery Associated AKI Trial (Prevent CSA-AKI Trial)

Quick Facts

Study Start:2024-07-18
Study Completion:2028-06-17
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06620523

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adult 18-70 years of age
  2. * Undergoing elective CPB (Cardiopulmonary Bypass) surgery
  3. * Baseline GFR (Glomerular Filtration Rate) ≥45 ml/min
  1. * GFR (Glomerular Filtration Rate) \<45 ml/min
  2. * Solitary kidney
  3. * Status post-kidney transplant
  4. * Pregnant women
  5. * Allergy to CoQ10
  6. * Allergy to Glutathione
  7. * Allergy to Cellulose

Contacts and Locations

Study Contact

Eduard Shaykhinurov, MS
CONTACT
2028234259
eshaykhinurov@mfa.gwu.edu
Yoosif Abdalla, MD
CONTACT

Principal Investigator

Yoosif Abdalla, MD
PRINCIPAL_INVESTIGATOR
George Washington University

Study Locations (Sites)

George Washington University Hospital
Washington, District of Columbia, 20037
United States

Collaborators and Investigators

Sponsor: George Washington University

  • Yoosif Abdalla, MD, PRINCIPAL_INVESTIGATOR, George Washington University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-07-18
Study Completion Date2028-06-17

Study Record Updates

Study Start Date2024-07-18
Study Completion Date2028-06-17

Terms related to this study

Keywords Provided by Researchers

  • cardiac surgery
  • critical care medicine
  • anesthesiology
  • nephrology
  • cardiopulmonary bypass
  • renal failure
  • aki
  • supplement

Additional Relevant MeSH Terms

  • Renal Failure
  • Coronary Artery Disease
  • Surgery
  • Surgery-Complications