RECRUITING

Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study aims to assess the levels of phosphorylated alpha-synuclein (P-SYN) in patients with Parkinson's disease and REM Behavior Disorder using a minimally invasive skin punch biopsy. It seeks to understand the natural progression of P-SYN deposition over time to explore the potential of P-SYN quantification as a biomarker for disease progression.

Official Title

Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease

Quick Facts

Study Start:2024-10
Study Completion:2026-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06621602

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years to 100 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Male and female 50 to 100 years of age
  2. 2. Clinical confirmed diagnosis of Parkinson\'s disease or REM Sleep Behavior
  1. 1. Clinical evidence of severe vascular disease (history of ulceration, poor wound healing or vascular claudication)
  2. 2. History of allergic reaction to Lidocaine for local anesthesia needed for skin biopsies
  3. 3. Use of blood thinners (Plavix or Aspirin used separately is allowed)
  4. 4. Significantly impaired wound healing or history of scarring or keloid formation

Contacts and Locations

Study Contact

Jade Clinical Research Program Manager
CONTACT
480-795-3437
jstohl@cndlifesciences.com

Principal Investigator

Todd Chief Medical Officer
PRINCIPAL_INVESTIGATOR
CND Life Sciences

Study Locations (Sites)

CND Life Sciences
Scottsdale, Arizona, 85258
United States

Collaborators and Investigators

Sponsor: CND Life Sciences

  • Todd Chief Medical Officer, PRINCIPAL_INVESTIGATOR, CND Life Sciences

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-10
Study Completion Date2026-04

Study Record Updates

Study Start Date2024-10
Study Completion Date2026-04

Terms related to this study

Keywords Provided by Researchers

  • PD
  • RBD

Additional Relevant MeSH Terms

  • REM Behavior Disorder
  • Parkinson Disease