Sevoflurane/Dexmedetomidine Vs. Isoflurane for Pediatric Emergence Delirium

Description

The purpose of this study is to measure the incidences of pediatric emergence delirium between the group receiving Isoflurane and the group receiving Sevoflurane plus intravenous push dexmedetomidine.

Conditions

Delirium on Emergence

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Study Overview

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Study Details

Study overview

The purpose of this study is to measure the incidences of pediatric emergence delirium between the group receiving Isoflurane and the group receiving Sevoflurane plus intravenous push dexmedetomidine.

Sevoflurane/Dexmedetomidine Vs. Isoflurane and Their Effects on Pediatric Emergence Delirium

Sevoflurane/Dexmedetomidine Vs. Isoflurane for Pediatric Emergence Delirium

Condition
Delirium on Emergence
Intervention / Treatment

-

Contacts and Locations

Rochester

Mayo Clinic in Rochester, Rochester, Minnesota, United States, 55905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Pediatric patients aged 2-7 years.
  • * Surgeries include ENT cases (i.e., tonsillectomy/adenoidectomy), ophthalmology cases (i.e., strabismus), and urology cases.
  • * Can be outpatient or General Care inpatient procedures.
  • * All cases must include an IV and an endotracheal tube (ETT).
  • * Severe developmental/cognitive delay (unable to make eye contact, nonverbal, or inability to interact with providers for PAED scale assessment requirements)
  • * TIVA cases.
  • * No PIV in place during the case, planned PICU admission postoperatively.
  • * Previous history of severe emergence delirium documented by a provider (via interventions or explicitly stated).

Ages Eligible for Study

2 Years to 7 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Mayo Clinic,

Lindsay Warner, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

2026-11-01