RECRUITING

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this observational study is to find out what factors affect the health and risks in adults with glioblastoma (GBM), a grade 4 brain cancer. The main questions it aims to answer are: * How do genetic and immune system factors impact survival and quality of life in GBM patients? * What occupational and medical history factors are linked to the risk of getting GBM? Participants will: * Fill out an online survey about their medical history and lifestyle. Participants will have the chance to give a blood sample (from the outer arm) for genetic and immune system testing. Blood samples will be given using a home collection kit provided by the study team.

Official Title

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

Quick Facts

Study Start:2024-12-10
Study Completion:2027-12-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06625684

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * At least 18 years old
  2. * Pathologically-confirmed diagnosis of glioblastoma multiforme (GBM) or grade 4 brain tumor
  3. * Participant is accessible for follow-up (has a working email address)
  4. * Participant is willing and able to comply with the study requirements
  1. * Those who cannot read either English or Spanish
  2. * Those who cannot view an online survey

Contacts and Locations

Study Contact

Courtney E Wimberly, MSc
CONTACT
919-681-9609
GBMsurvey@duke.edu

Principal Investigator

Kyle M Walsh, PhD
PRINCIPAL_INVESTIGATOR
Duke University

Study Locations (Sites)

Duke University
Durham, North Carolina, 27710
United States

Collaborators and Investigators

Sponsor: Duke University

  • Kyle M Walsh, PhD, PRINCIPAL_INVESTIGATOR, Duke University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-10
Study Completion Date2027-12-10

Study Record Updates

Study Start Date2024-12-10
Study Completion Date2027-12-10

Terms related to this study

Keywords Provided by Researchers

  • Glioblastoma
  • genetic predisposition to disease
  • risk factors
  • quality of life
  • questionnaires
  • blood sample
  • adult brain cancer
  • observational study
  • personal medical history
  • survival outcomes
  • cancer epidemiology
  • genetics, medical
  • immunologic factors
  • patient outcomes
  • health history
  • occupational exposure

Additional Relevant MeSH Terms

  • Glioblastoma