RECRUITING

Screening Strategies Among High-risk Populations for Anal Cancer

Description

The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.

Study Overview

Study Details

Study overview

The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.

Screening Strategies Among High-risk Populations for Anal Cancer

Screening Strategies Among High-risk Populations for Anal Cancer

Condition
Neoplasms
Intervention / Treatment

-

Contacts and Locations

Miami

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida, United States, 33136

Miami

University of Miami School of Medicine at Jackson Memorial Hospital (JMH), Miami, Florida, United States, 33136

Atlanta

Grady Memorial Hospital, Atlanta, Georgia, United States, 30303

Atlanta

The Ponce Center, Atlanta, Georgia, United States, 30308

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 30-80 years of age
  • * Individuals with chronic impaired immune status
  • * History of high-grade lower genital tract neoplasia (LGTN), Zubrod Performance Status of 0-2;
  • * Patients treated for aHSIL less than 6 months before screening,
  • * History of anal cancer and pregnant women.

Ages Eligible for Study

30 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Lisa Flowers,

Lisa Flowers, MD, MPH, PRINCIPAL_INVESTIGATOR, Emory University

Canhua Xiao, PhD, RN, PRINCIPAL_INVESTIGATOR, Emory University

Study Record Dates

2027-10