RECRUITING

Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

EGFR gene mutations are some of the most commonly occurring mutations in non-small cell lung cancer. Investigators have developed a DNA instability model that estimates a risk score to assess the likelihood of an individual acquiring a cancer-linked mutation. The aim of this study is to collect blood from both those diagnosed with EGFR positive lung cancer and healthy individuals, evaluate their gene sequence surrounding the EGFR landscape and use the cancer positive and healthy sequences to validate the risk assessment model, which may one day be used to provide insight on susceptibility of getting EGFR positive lung cancer or potentially other cancer types.

Official Title

Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients

Quick Facts

Study Start:2025-01-01
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06659458

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 100 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18-100 years old
  2. * Biologically born female
  3. * Diagnosed with EGFR positive lung cancer (Arm 1-Cancer group)
  4. * No cancer diagnosis (Arm 2-health control)
  1. * less than 18 years of age
  2. * Biologically born male
  3. * Incarcerated at the time of participation

Contacts and Locations

Study Contact

Cynthia Knox, MBA
CONTACT
225-765-3344
Cynthia.Knox@fmolhs.org
Christine LeBoeuf, DNP
CONTACT
225-763-5956
Christine.Leboeuf@fmolhs.org

Study Locations (Sites)

Our Lady of the Lake Regional Medical Center
Baton Rouge, Louisiana, 70808
United States

Collaborators and Investigators

Sponsor: Our Lady of the Lake Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-01
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2025-01-01
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • Lung cancer
  • EGFR gene

Additional Relevant MeSH Terms

  • Lung Cancer - Non Small Cell
  • EGFR Exon 19 Deletion Mutation