RECRUITING

Nutrient Profile and Muscle Protein Synthesis in Response to Corn Bread Made From Refined Versus Whole Grain Maize Flour

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of the study is to quantify and compare the serum nutrient and hormonal profile, and muscle protein synthesis rates, in response to consuming isonitrogenous amounts of a traditional East African meal, mung bean stew with a traditional African corn bread made from two different kinds of maize (whole corn flour or refined). Specific aim 1: Describe the post-prandial nutrient and hormonal profile in serum in the 3 hours following consumption of a portion of mung bean stew with traditional African corn bread made with either whole grain maize flour or refined maize flour. Specific aim 2: Compare the ability a portion of mung bean stew and traditional African corn bread made with either whole grain maize flour or refined maize flour to activate mTORC1-specific and whole muscle protein synthesis in an in vitro model of muscle.

Official Title

Nutrient Profile and Muscle Protein Synthesis in Response to Corn Bread Made From Refined Versus Whole Grain Maize Flour

Quick Facts

Study Start:2025-02-24
Study Completion:2026-06-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06662214

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 30 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Healthy active males and females (To be considered active, volunteers must meet the following American College of Sports Medicine's guideline for physical activity for healthy adults: performing at least 150 minutes per week of moderate-to-vigorous intensity physical activity.
  2. * Age18-30 years
  3. * Normal weight (BMI between 18 and 25 kg/m2
  1. * Health or dietary restrictions that would prevent consumption of the test foods
  2. * Known food allergy to corn
  3. * Anemia (low red blood cell count)
  4. * Overweight or obesity (BMI \> 25 kg/m2)
  5. * Receiving any medication that may interfere with the study
  6. * Metabolic or endocrine disorder that would affect the digestion, absorption, and/or physiological response to any of the nutrients ingested.
  7. * Currently not meeting the ACSM physical activity recommendations (IPAQ score \< 150 min/week of moderate-to-vigorous physical activity.
  8. * Pregnancy

Contacts and Locations

Study Contact

Emelie Strandberg, PhD
CONTACT
5307049253
ekstrandberg@ucdavis.edu
Keith Baar, PhD
CONTACT
kbaar@ucdavis.edu

Principal Investigator

Keith Baar
PRINCIPAL_INVESTIGATOR
University of California, Davis

Study Locations (Sites)

UC Davis CTSC Clinical Research Center
Sacramento, California, 95817
United States

Collaborators and Investigators

Sponsor: University of California, Davis

  • Keith Baar, PRINCIPAL_INVESTIGATOR, University of California, Davis

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-24
Study Completion Date2026-06-01

Study Record Updates

Study Start Date2025-02-24
Study Completion Date2026-06-01

Terms related to this study

Keywords Provided by Researchers

  • muscle protein synthesis
  • post-prandial nutrient and hormonal profile
  • farming practices

Additional Relevant MeSH Terms

  • Effect of Food