RECRUITING

GYNecologic Cancer-Related COGnitive Impairment

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Conditions

Ovarian CancerEndometrial CancerCervical CancersVulvar CancersUterine CancerCervix CancerOvary Cancercognitive impairmentgynecologic cancercancer related cognitive impairment

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to test a home-based and patient-tailored cognitive training intervention among gynecologic cancer patients who have completed chemotherapy and who have experienced cancer-related cognitive impairment.

Official Title

A Pilot and Mixed-Methods Study of GYNecologic Cancer-Related COGnitive Impairment

Quick Facts

Study Start:2025-02-07
Study Completion:2028-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06662435

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Female; ≥18 years of age
  2. * Presents to clinic with a confirmed diagnosis of a gynecologic cancer (e.g., ovarian, endometrial, cervical, or vulvar cancer) who have completed adjuvant chemotherapy with at least stable disease at time of screening.
  3. * Screen positive for subjective cognitive impairment by answering affirmatively to at least one of three screener questions
  4. * Fluent in spoken and written English
  5. * Have access to the internet to complete assessments
  1. * Patients who have not received chemotherapy
  2. * Patients with pre-existing neuropsychiatric disorders that would impact cognitive function, such as dementia, Alzheimer's disease, and schizophrenia.
  3. * Patients with non-gynecologic causes of incurable metastatic cancers.
  4. * Patients undergoing active interventions in other cognitive trials or patients currently using cognitive training programs such as Brain HQ, Luminosity, Elevate, Peak, Fit Brains, or CogniFit.
  5. * Patients with self-report of learning disability or an unwillingness to participate in technology-based cognitive training programs.
  6. * Pregnant women or prisoners
  7. * Patients with impaired-decision making capacity

Contacts and Locations

Study Contact

Anne Grace, PhD
CONTACT
312-503-4165
anne@northwestern.edu
Isabelle Kildee
CONTACT
312-472-5726
isabelle.kildee@northwestern.edu

Principal Investigator

Emma Barber, MD, MS
PRINCIPAL_INVESTIGATOR
Northwestern University

Study Locations (Sites)

Northwestern University
Chicago, Illinois, 60611
United States

Collaborators and Investigators

Sponsor: Northwestern University

  • Emma Barber, MD, MS, PRINCIPAL_INVESTIGATOR, Northwestern University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-07
Study Completion Date2028-12

Study Record Updates

Study Start Date2025-02-07
Study Completion Date2028-12

Terms related to this study

Keywords Provided by Researchers

  • cognitive impairment
  • gynecologic cancer
  • cancer related cognitive impairment

Additional Relevant MeSH Terms

  • Ovarian Cancer
  • Endometrial Cancer
  • Cervical Cancers
  • Vulvar Cancers
  • Uterine Cancer
  • Cervix Cancer
  • Ovary Cancer