SUSPENDED

Testing Low Dose Tamoxifen for Invasive Breast Cancer, the (LoTam) Trial

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Conditions

Anatomic Stage 0 Breast Cancer AJCC v8Anatomic Stage 1 Breast Cancer AJCC v8Anatomic Stage IIA Breast Cancer AJCC v8Estrogen Receptor-Positive Breast CarcinomaHER2-Negative Breast Carcinoma

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This phase III trial compares the effect of low dose tamoxifen to usual hormonal therapy, including aromatase inhibitors, in treating post-menopausal women with hormone positive, HER2 negative early stage breast cancer. Tamoxifen is in a class of medications known as antiestrogens. It blocks the activity of estrogen (a female hormone) in the breast. This may stop the growth of some breast tumors that need estrogen to grow. Aromatase inhibitors, such as anastrozole, letrozole, and exemestane, prevent the formation of estradiol, a female hormone, by interfering with an aromatase enzyme. Aromatase inhibitors are used as a type of hormone therapy to treat postmenopausal women with hormone-dependent breast cancer. Giving low dose tamoxifen may be more effective compared to usual hormone therapy in treating post-menopausal women with hormone-positive, HER2 negative early stage breast cancer.

Official Title

LoTam: A Randomized, Phase III Clinical Trial of Low-Dose Tamoxifen for Selected Patients With Molecular Low-Risk Early-Stage Breast Cancer

Quick Facts

Study Start:2025-02-19
Study Completion:2031-11-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:SUSPENDED

Study ID

NCT06671912

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Unilateral invasive adenocarcinoma of the breast that is histologically confirmed
  2. * Invasive breast cancer is estrogen receptor positive in ≥ 10% of cells
  3. * HER2 negative by current American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guidelines
  4. * The patient must have a multigene assay with a low-risk score, including any of the following (if more than one genomic assay was obtained, both are required to be low-risk):
  5. * Oncotype DX recurrence score ≤ 25
  6. * Mamma Print low risk
  7. * Prosigna risk of recurrence ≤ 40
  8. * Tumor size must be ≤ 3 cm by pathologic evaluation
  9. * Adequate surgical removal of all clinically evident disease in the breast with either breast conserving surgery or mastectomy. Negative margins on final pathology are required. Additional excisions may be performed to obtain clear margins before registration
  10. * No clinical (cN1, cN2, cN3) or pathologic (pN1mi, pN1, pN2, or pN3) evidence of lymph node involvement on either needle biopsy or surgical lymph node assessment. Patients with pN0(i+) or pN0 (mol+) are eligible
  11. * Surgical axillary staging (sentinel lymph node biopsy ± axillary lymph node dissection) is completed according to physician discretion
  12. * For patients with negative preoperative axillary ultrasonography, clinicians may selectively choose to forego surgical axillary staging. Ipsilateral axillary ultrasound showing no lymph node involvement with no evidence of lymphadenopathy or suspicious thickening is required in this scenario
  13. * No pathological tumor size \> 3 cm or pT4
  14. * No definitive clinical or radiologic evidence of metastatic disease
  15. * No palpable or radiographically suspicious axillary, supraclavicular, infraclavicular, or internal mammary lymph nodes, unless there is histologic confirmation that these lymph nodes are negative for tumor
  16. * No suspicious microcalcifications, densities, or palpable abnormalities in the ipsilateral or contralateral breast, unless biopsied and found to be benign
  17. * An interval of no more than 20 weeks between the date of surgery and the date of registration
  18. * Must have had a bilateral mammogram or MRI within 6 months prior to registration
  19. * Must be intending to take endocrine therapy for at least 5 years duration
  20. * No prior treatment with endocrine therapy or chemotherapy for the currently diagnosed breast cancer prior to registration. (Short course endocrine therapy of ≤ 6 weeks duration is acceptable after core biopsy and before surgery, if genomic testing is assessed on the biopsy core and meets eligibility requirements for a low-risk score.)
  21. * No use of oral hormone replacement therapy within 7 days prior to registration
  22. * Age ≥ 18 years
  23. * Eastern Cooperative Oncology Group (ECOG) performance status ≤ 2
  24. * Postmenopausal status confirmed as:
  25. * No spontaneous menses ≥ 1 year
  26. * No menses for \< 1 year with follicle stimulating hormone (FSH) and estradiol levels within a postmenopausal range according to institutional standards
  27. * Previous bilateral surgical oophorectomy
  28. * None of the following conditions:
  29. * Abnormal or dysfunctional uterine bleeding within 1 year prior to study enrollment
  30. * Any patient with known atypia or endometrial pathology that the opinion of the treating investigator would place the patient at undue risk of endometrial cancer with tamoxifen.
  31. * Any patient with a known hypercoagulable state that in the opinion of the treating investigator would put the patient at undue risk of venous thromboembolism with tamoxifen
  32. * No history of breast or thoracic radiotherapy for any previous condition. Patients may complete radiotherapy for the currently diagnosed breast cancer prior to registering for the study. In this scenario, registration must be completed within 12 weeks of completing breast radiotherapy
  33. * No previous history of ipsilateral invasive breast cancer or ipsilateral ductal carcinoma in situ (DCIS), regardless of the disease-free interval
  34. * No synchronous or previous contralateral invasive or non-invasive breast cancer
  35. * Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial
  36. * No patients with premenopausal status
  37. * No current treatment with any endocrine therapy for breast cancer prevention or osteoporosis, including raloxifene, tamoxifen, or other selective estrogen receptor modulator. Patients intending to continue oral hormone replacement are not eligible
  38. * HIV-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Locations (Sites)

Katmai Oncology Group
Anchorage, Alaska, 99508
United States
Arizona Center for Cancer Care - Gilbert
Gilbert, Arizona, 85297
United States
CTCA at Western Regional Medical Center
Goodyear, Arizona, 85338
United States
Arizona Center for Cancer Care-Peoria
Peoria, Arizona, 85381
United States
Arizona Center for Cancer Care - Biltmore
Phoenix, Arizona, 85016
United States
Arizona Center for Cancer Care - Phoenix
Phoenix, Arizona, 85027
United States
Mayo Clinic Hospital in Arizona
Phoenix, Arizona, 85054
United States
Arizona Center for Cancer Care - Osborn
Scottsdale, Arizona, 85251
United States
Arizona Center for Cancer Care - Scottsdale
Scottsdale, Arizona, 85258
United States
Arizona Center for Cancer Care-Surprise
Surprise, Arizona, 85374
United States
Arizona Center for Cancer Care
Tempe, Arizona, 85284
United States
Mercy Hospital Fort Smith
Fort Smith, Arkansas, 72903
United States
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro, Arkansas, 72401
United States
UCSF Cancer Center - Berkeley
Berkeley, California, 94702
United States
Tower Cancer Research Foundation
Beverly Hills, California, 90211
United States
Keck Medicine of USC Buena Park
Buena Park, California, 90621
United States
Marshall Cancer Center
Cameron Park, California, 95682
United States
Mercy Cancer Center - Carmichael
Carmichael, California, 95608
United States
Mercy San Juan Medical Center
Carmichael, California, 95608
United States
Enloe Medical Center
Chico, California, 95926
United States
City of Hope Corona
Corona, California, 92882
United States
City of Hope Comprehensive Cancer Center
Duarte, California, 91010
United States
Kaiser Permanente Dublin
Dublin, California, 94568
United States
Mercy Cancer Center - Elk Grove
Elk Grove, California, 95758
United States
Stanford Cancer Center Emeryville
Emeryville, California, 94608
United States
Kaiser Permanente-Fremont
Fremont, California, 94538
United States
Washington Hospital
Fremont, California, 94538
United States
Kaiser Permanente Fresno Orchard Plaza
Fresno, California, 93720
United States
Kaiser Permanente-Fresno
Fresno, California, 93720
United States
City of Hope Seacliff
Huntington Beach, California, 92648
United States
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, 92612
United States
City of Hope at Irvine Lennar
Irvine, California, 92618
United States
UC San Diego Moores Cancer Center
La Jolla, California, 92093
United States
City of Hope Antelope Valley
Lancaster, California, 93534
United States
Loma Linda University Medical Center
Loma Linda, California, 92354
United States
City of Hope at Long Beach Elm
Long Beach, California, 90813
United States
Los Angeles General Medical Center
Los Angeles, California, 90033
United States
USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033
United States
Cedars Sinai Medical Center
Los Angeles, California, 90048
United States
Fremont - Rideout Cancer Center
Marysville, California, 95901
United States
Kaiser Permanente- Modesto MOB II
Modesto, California, 95356
United States
Kaiser Permanente-Modesto
Modesto, California, 95356
United States
City of Hope Newport Beach
Newport Beach, California, 92660
United States
USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, 92663
United States
Kaiser Permanente-Oakland
Oakland, California, 94611
United States
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868
United States
Stanford Cancer Institute Palo Alto
Palo Alto, California, 94304
United States
Huntington Memorial Hospital
Pasadena, California, 91105
United States
Eisenhower Medical Center
Rancho Mirage, California, 92270
United States
Mercy Cancer Center - Rocklin
Rocklin, California, 95765
United States
Kaiser Permanente-Roseville
Roseville, California, 95661
United States
Kaiser Permanente Downtown Commons
Sacramento, California, 95814
United States
Mercy Cancer Center - Sacramento
Sacramento, California, 95816
United States
University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817
United States
Kaiser Permanente-South Sacramento
Sacramento, California, 95823
United States
UC San Diego Medical Center - Hillcrest
San Diego, California, 92103
United States
Sharp Memorial Hospital
San Diego, California, 92123
United States
Zuckerberg San Francisco General Hospital
San Francisco, California, 94110
United States
Kaiser Permanente-San Francisco
San Francisco, California, 94115
United States
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, 95119
United States
Stanford Cancer Center South Bay
San Jose, California, 95124
United States
Kaiser Permanente San Leandro
San Leandro, California, 94577
United States
Kaiser San Rafael-Gallinas
San Rafael, California, 94903
United States
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, 95051
United States
Kaiser Permanente-Santa Rosa
Santa Rosa, California, 95403
United States
Providence Medical Foundation - Santa Rosa
Santa Rosa, California, 95403
United States
Providence Santa Rosa Memorial Hospital
Santa Rosa, California, 95405
United States
City of Hope South Pasadena
South Pasadena, California, 91030
United States
Kaiser Permanente-South San Francisco
South San Francisco, California, 94080
United States
Saint Helena Hospital
St. Helena, California, 94574
United States
Cedars-Sinai Cancer - Tarzana
Tarzana, California, 91356
United States
City of Hope South Bay
Torrance, California, 90503
United States
Torrance Memorial Physician Network - Cancer Care
Torrance, California, 90505
United States
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California, 96161
United States
City of Hope Upland
Upland, California, 91786
United States
Kaiser Permanente-Vallejo
Vallejo, California, 94589
United States
Kaiser Permanente-Walnut Creek
Walnut Creek, California, 94596
United States
Woodland Memorial Hospital
Woodland, California, 95695
United States
UCI Health - Yorba Linda
Yorba Linda, California, 92886
United States
UCHealth University of Colorado Hospital
Aurora, Colorado, 80045
United States
Intermountain Health Platte Valley Hospital
Brighton, Colorado, 80601
United States
UCHealth Memorial Hospital Central
Colorado Springs, Colorado, 80909
United States
Memorial Hospital North
Colorado Springs, Colorado, 80920
United States
UCHealth - Cherry Creek
Denver, Colorado, 80206
United States
Saint Joseph Hospital - Cancer Centers of Colorado
Denver, Colorado, 80218
United States
Shaw Cancer Center
Edwards, Colorado, 81632
United States
Poudre Valley Hospital
Fort Collins, Colorado, 80524
United States
Cancer Care and Hematology-Fort Collins
Fort Collins, Colorado, 80528
United States
Lutheran Hospital - Cancer Centers of Colorado
Golden, Colorado, 80401
United States
Saint Mary's Hospital and Regional Medical Center
Grand Junction, Colorado, 81501
United States
UCHealth Greeley Hospital
Greeley, Colorado, 80631
United States
UCHealth Highlands Ranch Hospital
Highlands Ranch, Colorado, 80129
United States
Good Samaritan Hospital - Cancer Centers of Colorado
Lafayette, Colorado, 80026
United States
UCHealth Lone Tree Health Center
Lone Tree, Colorado, 80124
United States
Medical Center of the Rockies
Loveland, Colorado, 80538
United States
Saint Anthony North Hospital
Westminster, Colorado, 80023
United States
Danbury Hospital
Danbury, Connecticut, 06810
United States
Smilow Cancer Hospital-Derby Care Center
Derby, Connecticut, 06418
United States
Smilow Cancer Hospital Care Center-Fairfield
Fairfield, Connecticut, 06824
United States
Smilow Cancer Hospital Care Center at Glastonbury
Glastonbury, Connecticut, 06033
United States
Smilow Cancer Hospital Care Center at Greenwich
Greenwich, Connecticut, 06830
United States
Smilow Cancer Hospital Care Center - Guilford
Guilford, Connecticut, 06437
United States
Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut, 06105
United States
Yale University
New Haven, Connecticut, 06520
United States
Yale-New Haven Hospital North Haven Medical Center
North Haven, Connecticut, 06473
United States
Norwalk Hospital
Norwalk, Connecticut, 06856
United States
Smilow Cancer Hospital Care Center at Long Ridge
Stamford, Connecticut, 06902
United States
Stamford Hospital/Bennett Cancer Center
Stamford, Connecticut, 06904
United States
Smilow Cancer Hospital-Torrington Care Center
Torrington, Connecticut, 06790
United States
Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut, 06611
United States
Smilow Cancer Hospital-Waterbury Care Center
Waterbury, Connecticut, 06708
United States
Smilow Cancer Hospital Care Center - Waterford
Waterford, Connecticut, 06385
United States
Bayhealth Hospital Kent Campus
Dover, Delaware, 19901
United States
Bayhealth Hospital Sussex Campus
Milford, Delaware, 19963
United States
Beebe South Coastal Health Campus
Millville, Delaware, 19967
United States
Helen F Graham Cancer Center
Newark, Delaware, 19713
United States
Medical Oncology Hematology Consultants PA
Newark, Delaware, 19713
United States
Beebe Health Campus
Rehoboth Beach, Delaware, 19971
United States
Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware, 19801
United States
Kaiser Permanente-Capitol Hill Medical Center
Washington D.C., District of Columbia, 20002
United States
Morton Plant Hospital
Clearwater, Florida, 33756
United States
UM Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, 33146
United States
UM Sylvester Comprehensive Cancer Center at Coral Springs
Coral Springs, Florida, 33065
United States
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, 33442
United States
UM Sylvester Comprehensive Cancer Center at Doral
Doral, Florida, 33166
United States
UF Health Cancer Institute - Gainesville
Gainesville, Florida, 32610
United States
Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980
United States
Jupiter Medical Center
Jupiter, Florida, 33458
United States
The Watson Clinic
Lakeland, Florida, 33805
United States
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136
United States
UM Sylvester Comprehensive Cancer Center at Kendall
Miami, Florida, 33176
United States
Mount Sinai Medical Center
Miami Beach, Florida, 33140
United States
University of Miami Sylvester Comprehensive Cancer Center at Sole Mia
North Miami, Florida, 33181
United States
UM Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida, 33324
United States
Mease Countryside Hospital
Safety Harbor, Florida, 34695
United States
Saint Anthony's Hospital Cancer Care Center
St. Petersburg, Florida, 33705
United States
Winter Haven Hospital
Winter Haven, Florida, 33881
United States
Phoebe Putney Memorial Hospital
Albany, Georgia, 31701
United States
University Cancer and Blood Center LLC
Athens, Georgia, 30607
United States
Hamilton Medical Center - Peeples Cancer Institute
Dalton, Georgia, 30720
United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah, Georgia, 31405
United States
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii, 96813
United States
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii, 96813
United States
Queen's Medical Center
Honolulu, Hawaii, 96813
United States
Straub Clinic and Hospital
Honolulu, Hawaii, 96813
United States
Queen's Cancer Center - Kuakini
Honolulu, Hawaii, 96817
United States
Kaiser Permanente Moanalua Medical Center
Honolulu, Hawaii, 96819
United States
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, 96826
United States
Hawaii Cancer Care - Westridge
‘Aiea, Hawaii, 96701
United States
Pali Momi Medical Center
‘Aiea, Hawaii, 96701
United States
The Queen's Medical Center - West Oahu
‘Ewa Beach, Hawaii, 96706
United States
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, 83706
United States
Saint Luke's Cancer Institute - Boise
Boise, Idaho, 83712
United States
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho, 83605
United States
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho, 83814
United States
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho, 83619
United States
Idaho Urologic Institute-Meridian
Meridian, Idaho, 83642
United States
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho, 83642
United States
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho, 83687
United States
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho, 83687
United States
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, 83854
United States
Kootenai Clinic Cancer Services - Sandpoint
Sandpoint, Idaho, 83864
United States
Rush-Copley Medical Center
Aurora, Illinois, 60504
United States
Advocate Outpatient Center - Aurora
Aurora, Illinois, 60506
United States
Advocate Good Shepherd Hospital
Barrington, Illinois, 60010
United States
Illinois CancerCare-Bloomington
Bloomington, Illinois, 61704
United States
Illinois CancerCare-Canton
Canton, Illinois, 61520
United States
Illinois CancerCare-Carthage
Carthage, Illinois, 62321
United States
Mount Sinai Hospital Medical Center
Chicago, Illinois, 60608
United States
Northwestern University
Chicago, Illinois, 60611
United States
John H Stroger Jr Hospital of Cook County
Chicago, Illinois, 60612
United States
University of Illinois
Chicago, Illinois, 60612
United States
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637
United States
Advocate Illinois Masonic Medical Center
Chicago, Illinois, 60657
United States
AMG Crystal Lake - Oncology
Crystal Lake, Illinois, 60014
United States
Carle at The Riverfront
Danville, Illinois, 61832
United States
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, 62526
United States
Decatur Memorial Hospital
Decatur, Illinois, 62526
United States
Northwestern Medicine Cancer Center Kishwaukee
DeKalb, Illinois, 60115
United States
Illinois CancerCare-Dixon
Dixon, Illinois, 61021
United States
Advocate Good Samaritan Hospital
Downers Grove, Illinois, 60515
United States
Carle Physician Group-Effingham
Effingham, Illinois, 62401
United States
Crossroads Cancer Center
Effingham, Illinois, 62401
United States
Advocate Sherman Hospital
Elgin, Illinois, 60123
United States
Illinois CancerCare-Eureka
Eureka, Illinois, 61530
United States
Illinois CancerCare-Galesburg
Galesburg, Illinois, 61401
United States
Northwestern Medicine Cancer Center Delnor
Geneva, Illinois, 60134
United States
Northwestern Medicine Glenview Outpatient Center
Glenview, Illinois, 60026
United States
Northwestern Medicine Grayslake Outpatient Center
Grayslake, Illinois, 60030
United States
Ingalls Memorial Hospital
Harvey, Illinois, 60426
United States
Advocate South Suburban Hospital
Hazel Crest, Illinois, 60429
United States
UChicago Medicine AdventHealth Cancer Institute Hinsdale
Hinsdale, Illinois, 60521
United States
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, 61443
United States
Northwestern Medicine Lake Forest Hospital
Lake Forest, Illinois, 60045
United States
AMG Libertyville - Oncology
Libertyville, Illinois, 60048
United States
Condell Memorial Hospital
Libertyville, Illinois, 60048
United States
Illinois CancerCare-Macomb
Macomb, Illinois, 61455
United States
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, 61938
United States
Loyola University Medical Center
Maywood, Illinois, 60153
United States
Trinity Medical Center
Moline, Illinois, 61265
United States
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, 60451
United States
Carle BroMenn Medical Center
Normal, Illinois, 61761
United States
Carle Cancer Institute Normal
Normal, Illinois, 61761
United States
Cancer Care Center of O'Fallon
O'Fallon, Illinois, 62269
United States
Northwestern Medicine Oak Brook
Oak Brook, Illinois, 60523
United States
Advocate Christ Medical Center
Oak Lawn, Illinois, 60453-2699
United States
Advocate Outpatient Center - Oak Lawn
Oak Lawn, Illinois, 60453
United States
Northwestern Medicine Orland Park
Orland Park, Illinois, 60462
United States
University of Chicago Medicine-Orland Park
Orland Park, Illinois, 60462
United States
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, 61350
United States
Advocate High Tech Medical Park
Palos Heights, Illinois, 60463
United States
Advocate Lutheran General Hospital
Park Ridge, Illinois, 60068
United States
Illinois CancerCare-Pekin
Pekin, Illinois, 61554
United States
Illinois CancerCare-Peoria
Peoria, Illinois, 61615
United States
Illinois CancerCare-Peru
Peru, Illinois, 61354
United States
Illinois CancerCare-Princeton
Princeton, Illinois, 61356
United States
OSF Saint Anthony Medical Center
Rockford, Illinois, 61108
United States
UW Health Carbone Cancer Center Rockford
Rockford, Illinois, 61114
United States
Memorial Hospital East
Shiloh, Illinois, 62269
United States
Southern Illinois University School of Medicine
Springfield, Illinois, 62702
United States
Springfield Clinic
Springfield, Illinois, 62702
United States
Springfield Memorial Hospital
Springfield, Illinois, 62781
United States
Carle Cancer Center
Urbana, Illinois, 61801
United States
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois, 60555
United States
Illinois CancerCare - Washington
Washington, Illinois, 61571
United States
Rush-Copley Healthcare Center
Yorkville, Illinois, 60560
United States
Midwestern Regional Medical Center
Zion, Illinois, 60099
United States
IU Health West Hospital
Avon, Indiana, 46123
United States
IU Health North Hospital
Carmel, Indiana, 46032
United States
Northwest Cancer Center - Main Campus
Crown Point, Indiana, 46307
United States
UChicago Medicine Northwest Indiana
Crown Point, Indiana, 46307
United States
Northwest Oncology LLC
Dyer, Indiana, 46311
United States
Northwest Cancer Center - Hobart
Hobart, Indiana, 46342
United States
Saint Mary Medical Center
Hobart, Indiana, 46342
United States
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, 46202
United States
Saint Catherine Hospital
Indianapolis, Indiana, 46312
United States
The Community Hospital
Munster, Indiana, 46321
United States
Women's Diagnostic Center - Munster
Munster, Indiana, 46321
United States
Memorial Hospital of South Bend
South Bend, Indiana, 46601
United States
Northwest Cancer Center - Valparaiso
Valparaiso, Indiana, 46383
United States
Mary Greeley Medical Center
Ames, Iowa, 50010
United States
McFarland Clinic - Ames
Ames, Iowa, 50010
United States
UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny, Iowa, 50023
United States
University of Iowa Healthcare Cancer Services Quad Cities
Bettendorf, Iowa, 52722
United States
McFarland Clinic - Boone
Boone, Iowa, 50036
United States
Saint Anthony Regional Hospital
Carroll, Iowa, 51401
United States
Mercy Hospital
Cedar Rapids, Iowa, 52403
United States
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa, 52403
United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive, Iowa, 50325
United States
Iowa Methodist Medical Center
Des Moines, Iowa, 50309
United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa, 50309
United States
Broadlawns Medical Center
Des Moines, Iowa, 50314
United States
UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines, Iowa, 50314
United States
McFarland Clinic - Trinity Cancer Center
Fort Dodge, Iowa, 50501
United States
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, 52242
United States
McFarland Clinic - Jefferson
Jefferson, Iowa, 50129
United States
McFarland Clinic - Marshalltown
Marshalltown, Iowa, 50158
United States
UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee, Iowa, 50263
United States
HaysMed
Hays, Kansas, 67601
United States
University of Kansas Cancer Center
Kansas City, Kansas, 66160
United States
Lawrence Memorial Hospital
Lawrence, Kansas, 66044
United States
The University of Kansas Cancer Center - Olathe
Olathe, Kansas, 66061
United States
University of Kansas Cancer Center-Overland Park
Overland Park, Kansas, 66210
United States
University of Kansas Hospital-Indian Creek Campus
Overland Park, Kansas, 66211
United States
Salina Regional Health Center
Salina, Kansas, 67401
United States
University of Kansas Health System Saint Francis Campus
Topeka, Kansas, 66606
United States
University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas, 66205
United States
Saint Joseph Hospital East
Lexington, Kentucky, 40509
United States
The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky, 40202
United States
Baptist Health Louisville
Louisville, Kentucky, 40207
United States
UofL Health Medical Center Northeast
Louisville, Kentucky, 40245
United States
Louisiana Hematology Oncology Associates LLC
Baton Rouge, Louisiana, 70809
United States
Northshore Oncology Associates-Covington
Covington, Louisiana, 70433
United States
Ochsner Hematology Oncology North Shore - Covington (West Region)
Covington, Louisiana, 70433
United States
West Jefferson Medical Center
Marrero, Louisiana, 70072
United States
University Medical Center New Orleans
New Orleans, Louisiana, 70112
United States
Ochsner Medical Center Jefferson
New Orleans, Louisiana, 70121
United States
Harold Alfond Center for Cancer Care
Augusta, Maine, 04330
United States
Lafayette Family Cancer Center-EMMC
Brewer, Maine, 04412
United States
MaineHealth Cancer Care and IV Therapy - Brunswick
Brunswick, Maine, 04011
United States
Mid Coast Hospital
Brunswick, Maine, 04011
United States
Penobscot Bay Medical Center
Rockport, Maine, 04856
United States
MaineHealth Cancer Care and IV Therapy - Sanford
Sanford, Maine, 04073
United States
MaineHealth Cancer Care Center of York County
Sanford, Maine, 04073
United States
MaineHealth Cancer Care and IV Therapy - South Portland
South Portland, Maine, 04106
United States
UM Upper Chesapeake Hematology and Oncology - Aberdeen
Aberdeen, Maryland, 21001
United States
University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201
United States
Greater Baltimore Medical Center
Baltimore, Maryland, 21204
United States
Sinai Hospital of Baltimore
Baltimore, Maryland, 21215
United States
Kaiser Permanente-Woodlawn Medical Center
Baltimore, Maryland, 21244
United States
UM Upper Chesapeake Medical Center
Bel Air, Maryland, 21014
United States
Walter Reed National Military Medical Center
Bethesda, Maryland, 20889-5600
United States
UPMC Western Maryland
Cumberland, Maryland, 21502
United States
Kaiser Permanente-Gaithersburg Medical Center
Gaithersburg, Maryland, 20879
United States
Kaiser Permanente - Largo Medical Center
Largo, Maryland, 20774
United States
Kaiser Permanente Lutherville - Timonium Medical Center
Lutherville, Maryland, 21093
United States
William E Kahlert Regional Cancer Center/Sinai Hospital
Westminster, Maryland, 21157
United States
Beverly Hospital
Beverly, Massachusetts, 01915
United States
Tufts Medical Center
Boston, Massachusetts, 02111
United States
Lahey Hospital and Medical Center
Burlington, Massachusetts, 01805
United States
Addison Gilbert Hospital
Gloucester, Massachusetts, 01930
United States
Lowell General Hospital
Lowell, Massachusetts, 01854
United States
Lahey Medical Center-Peabody
Peabody, Massachusetts, 01960
United States
Tufts Medical Center Cancer Center Stoneham
Stoneham, Massachusetts, 02180
United States
University of Michigan Rogel Cancer Center
Ann Arbor, Michigan, 48109
United States
Bronson Battle Creek
Battle Creek, Michigan, 49017
United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton, Michigan, 48114
United States
University of Michigan - Brighton Center for Specialty Care
Brighton, Michigan, 48116
United States
Henry Ford Cancer Institute-Downriver
Brownstown, Michigan, 48183
United States
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton, Michigan, 48188
United States
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea, Michigan, 48118
United States
Michigan Healthcare Professionals Clarkston
Clarkston, Michigan, 48346
United States
Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan, 48038
United States
Henry Ford Medical Center-Fairlane
Dearborn, Michigan, 48126
United States
Henry Ford Hospital
Detroit, Michigan, 48202
United States
Henry Ford Health Saint John Hospital
Detroit, Michigan, 48236
United States
Henry Ford River District Hospital
East China Township, Michigan, 48054
United States
OSF Saint Francis Hospital and Medical Group
Escanaba, Michigan, 49829
United States
Michigan Healthcare Professionals Farmington
Farmington Hills, Michigan, 48334
United States
Cancer Hematology Centers - Flint
Flint, Michigan, 48503
United States
Genesee Hematology Oncology PC
Flint, Michigan, 48503
United States
Genesys Hurley Cancer Institute
Flint, Michigan, 48503
United States
Hurley Medical Center
Flint, Michigan, 48503
United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital
Grand Rapids, Michigan, 49503
United States
Trinity Health Grand Rapids Hospital
Grand Rapids, Michigan, 49503
United States
Henry Ford Saint John Hospital - Academic
Grosse Pointe Woods, Michigan, 48236
United States
Henry Ford Saint John Hospital - Breast
Grosse Pointe Woods, Michigan, 48236
United States
Henry Ford Saint John Hospital - Van Elslander
Grosse Pointe Woods, Michigan, 48236
United States
Allegiance Health
Jackson, Michigan, 49201
United States
Bronson Methodist Hospital
Kalamazoo, Michigan, 49007
United States
West Michigan Cancer Center
Kalamazoo, Michigan, 49007
United States
University of Michigan Health - Sparrow Lansing
Lansing, Michigan, 48912
United States
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia, Michigan, 48154
United States
Henry Ford Saint John Hospital - Macomb Medical
Macomb, Michigan, 48044
United States
Henry Ford Warren Hospital - Breast Macomb
Macomb, Michigan, 48044
United States
Michigan Healthcare Professionals Madison Heights
Madison Heights, Michigan, 48071
United States
MyMichigan Medical Center Midland
Midland, Michigan, 48670
United States
Trinity Health Muskegon Hospital
Muskegon, Michigan, 49444
United States
Corewell Health Lakeland Hospitals - Niles Hospital
Niles, Michigan, 49120
United States
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores, Michigan, 49444
United States
Henry Ford Medical Center-Columbus
Novi, Michigan, 48377
United States
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan, 48341
United States
Corewell Health Reed City Hospital
Reed City, Michigan, 49677
United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
Saint Joseph, Michigan, 49085
United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital
Saint Joseph, Michigan, 49085
United States
Munson Medical Center
Traverse City, Michigan, 49684
United States
Michigan Healthcare Professionals Troy
Troy, Michigan, 48098
United States
Henry Ford Health Warren Hospital
Warren, Michigan, 48093
United States
Henry Ford Madison Heights Hospital - Breast
Warren, Michigan, 48093
United States
Henry Ford Warren Hospital - GLCMS
Warren, Michigan, 48093
United States
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan, 48322
United States
Henry Ford Wyandotte Hospital
Wyandotte, Michigan, 48192
United States
University of Michigan Health - West
Wyoming, Michigan, 49519
United States
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti, Michigan, 48197
United States
Mayo Clinic Health System in Albert Lea
Albert Lea, Minnesota, 56007
United States
Sanford Joe Lueken Cancer Center
Bemidji, Minnesota, 56601
United States
Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota, 56401
United States
Minnesota Oncology - Burnsville
Burnsville, Minnesota, 55337
United States
Mercy Hospital
Coon Rapids, Minnesota, 55433
United States
Essentia Health - Deer River Clinic
Deer River, Minnesota, 56636
United States
Essentia Health Cancer Center
Duluth, Minnesota, 55805
United States
Saint Luke's Hospital of Duluth
Duluth, Minnesota, 55805
United States
Fairview Southdale Hospital
Edina, Minnesota, 55435
United States
Essentia Health Hibbing Clinic
Hibbing, Minnesota, 55746
United States
Mayo Clinic Health Systems-Mankato
Mankato, Minnesota, 56001
United States
Saint John's Hospital - Healtheast
Maplewood, Minnesota, 55109
United States
Abbott-Northwestern Hospital
Minneapolis, Minnesota, 55407
United States
Hennepin County Medical Center
Minneapolis, Minnesota, 55415
United States
New Ulm Medical Center
New Ulm, Minnesota, 56073
United States
North Memorial Medical Health Center
Robbinsdale, Minnesota, 55422
United States
Mayo Clinic in Rochester
Rochester, Minnesota, 55905
United States
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota, 56303
United States
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, 55416
United States
Regions Hospital
Saint Paul, Minnesota, 55101
United States
United Hospital
Saint Paul, Minnesota, 55102
United States
Essentia Health Sandstone
Sandstone, Minnesota, 55072
United States
Saint Francis Regional Medical Center
Shakopee, Minnesota, 55379
United States
Essentia Health Virginia Clinic
Virginia, Minnesota, 55792
United States
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota, 55125
United States
Baptist Memorial Hospital and Cancer Center-Golden Triangle
Columbus, Mississippi, 39705
United States
Baptist Cancer Center-Grenada
Grenada, Mississippi, 38901
United States
Baptist Memorial Hospital and Cancer Center-Union County
New Albany, Mississippi, 38652
United States
Baptist Memorial Hospital and Cancer Center-Oxford
Oxford, Mississippi, 38655
United States
Baptist Memorial Hospital and Cancer Center-Desoto
Southhaven, Mississippi, 38671
United States
Mercy Oncology and Hematology - Clayton-Clarkson
Ballwin, Missouri, 63011
United States
Saint Francis Medical Center
Cape Girardeau, Missouri, 63703
United States
Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters, Missouri, 63376
United States
Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri, 63141
United States
Parkland Health Center - Farmington
Farmington, Missouri, 63640
United States
Mercy Hospital Joplin
Joplin, Missouri, 64804
United States
University Health Truman Medical Center
Kansas City, Missouri, 64108
United States
University of Kansas Cancer Center - Briarcliff
Kansas City, Missouri, 64116
United States
University of Kansas Cancer Center - North
Kansas City, Missouri, 64154
United States
University of Kansas Cancer Center - Lee's Summit
Lee's Summit, Missouri, 64064
United States
Lake Regional Hospital
Osage Beach, Missouri, 65065
United States
Heartland Regional Medical Center
Saint Joseph, Missouri, 64506
United States
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri, 63670
United States
Washington University School of Medicine
St Louis, Missouri, 63110
United States
Mercy Hospital South
St Louis, Missouri, 63128
United States
Siteman Cancer Center-South County
St Louis, Missouri, 63129
United States
Missouri Baptist Medical Center
St Louis, Missouri, 63131
United States
Siteman Cancer Center at Christian Hospital
St Louis, Missouri, 63136
United States
Mercy Hospital Saint Louis
St Louis, Missouri, 63141
United States
Missouri Baptist Sullivan Hospital
Sullivan, Missouri, 63080
United States
BJC Outpatient Center at Sunset Hills
Sunset Hills, Missouri, 63127
United States
Community Hospital of Anaconda
Anaconda, Montana, 59711
United States
Billings Clinic Cancer Center
Billings, Montana, 59101
United States
Saint Vincent Frontier Cancer Center
Billings, Montana, 59102
United States
Bozeman Health Deaconess Hospital
Bozeman, Montana, 59715
United States
Benefis Sletten Cancer Institute
Great Falls, Montana, 59405
United States
Logan Health Medical Center
Kalispell, Montana, 59901
United States
Saint Patrick Hospital - Community Hospital
Missoula, Montana, 59802
United States
Community Medical Center
Missoula, Montana, 59804
United States
Nebraska Medicine-Bellevue
Bellevue, Nebraska, 68123
United States
Fred and Pamela Buffett Cancer Center - Kearney
Kearney, Nebraska, 68845
United States
Nebraska Medicine-Village Pointe
Omaha, Nebraska, 68118
United States
University of Nebraska Medical Center
Omaha, Nebraska, 68198
United States
New Hampshire Oncology Hematology PA-Concord
Concord, New Hampshire, 03301
United States
Solinsky Center for Cancer Care
Manchester, New Hampshire, 03103
United States
AtlantiCare Health Park-Cape May Court House
Cape May Court House, New Jersey, 08210
United States
Jefferson Cherry Hill Hospital
Cherry Hill, New Jersey, 08002
United States
AtlantiCare Surgery Center
Egg Harbor, New Jersey, 08234
United States
Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus
Elizabeth, New Jersey, 07207
United States
CentraState Medical Center
Freehold, New Jersey, 07728
United States
Hackensack University Medical Center
Hackensack, New Jersey, 07601
United States
The Cancer Institute of New Jersey Hamilton
Hamilton, New Jersey, 08690
United States
Jersey City Medical Center
Jersey City, New Jersey, 07302
United States
Monmouth Medical Center
Long Branch, New Jersey, 07740
United States
Morristown Medical Center
Morristown, New Jersey, 07960
United States
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903
United States
Newark Beth Israel Medical Center
Newark, New Jersey, 07112
United States
The Valley Hospital - Luckow Pavilion
Paramus, New Jersey, 07652
United States
Valley Health System Ridgewood Campus
Ridgewood, New Jersey, 07450
United States
Sidney Kimmel Cancer Center Washington Township
Sewell, New Jersey, 08080
United States
Robert Wood Johnson University Hospital Somerset
Somerville, New Jersey, 08876
United States
Overlook Hospital
Summit, New Jersey, 07902
United States
Holy Name Hospital
Teaneck, New Jersey, 07666
United States
Community Medical Center
Toms River, New Jersey, 08755
United States
Lovelace Medical Center-Saint Joseph Square
Albuquerque, New Mexico, 87102
United States
University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106
United States
Lovelace Women's Hospital
Albuquerque, New Mexico, 87109
United States
Presbyterian Kaseman Hospital
Albuquerque, New Mexico, 87110
United States
Presbyterian Rust Medical Center/Jorgensen Cancer Center
Rio Rancho, New Mexico, 87124
United States
Northwell Health Imbert Cancer Center
Bay Shore, New York, 11706
United States
New York-Presbyterian/Brooklyn Methodist Hospital
Brooklyn, New York, 11215
United States
Roswell Park Cancer Institute
Buffalo, New York, 14263
United States
Hematology Oncology Associates of CNY at Camillus
Camillus, New York, 13031
United States
Hematology Oncology Associates of Central New York-East Syracuse
East Syracuse, New York, 13057
United States
The New York Hospital Medical Center of Queens
Flushing, New York, 11355
United States
Glens Falls Hospital
Glens Falls, New York, 12801
United States
Northwell Health Cancer Institute at Huntington
Greenlawn, New York, 11740
United States
Northwell Health/Center for Advanced Medicine
Lake Success, New York, 11042
United States
Northern Westchester Hospital
Mount Kisco, New York, 10549
United States
Mount Sinai Chelsea
New York, New York, 10011
United States
Mount Sinai West
New York, New York, 10019
United States
Mount Sinai Hospital
New York, New York, 10029
United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032
United States
Manhattan Eye Ear and Throat Hospital
New York, New York, 10065
United States
NYP/Weill Cornell Medical Center
New York, New York, 10065
United States
Lenox Hill Hospital
New York, New York, 10075
United States
Vassar Brothers Medical Center
Poughkeepsie, New York, 12601
United States
Queens Cancer Center
Rego Park, New York, 11374
United States
Pluta Cancer Center
Rochester, New York, 14623
United States
Phelps Memorial Hospital Center
Sleepy Hollow, New York, 10591
United States
The Philips Family Cancer Center
Southampton, New York, 11968
United States
Stony Brook University Medical Center
Stony Brook, New York, 11794
United States
Wilmot Cancer Institute at Webster
Webster, New York, 14580
United States
Dickstein Cancer Treatment Center
White Plains, New York, 10601
United States
AdventHealth Infusion Center Asheville
Asheville, North Carolina, 28803
United States
Duke Cancer Center Cary
Cary, North Carolina, 27518
United States
Waverly Hematology Oncology
Cary, North Carolina, 27518
United States
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599
United States
Novant Health Presbyterian Medical Center
Charlotte, North Carolina, 28204
United States
Wake Forest University at Clemmons
Clemmons, North Carolina, 27012
United States
AdventHealth Infusion Center Haywood
Clyde, North Carolina, 28721
United States
Duke University Medical Center
Durham, North Carolina, 27710
United States
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina, 28791
United States
AdventHealth Hendersonville
Hendersonville, North Carolina, 28792
United States
University of North Carolina-Hillsborough Campus
Hillsborough, North Carolina, 27278
United States
Novant Health Cancer Institute - Huntersville
Huntersville, North Carolina, 28078
United States
Novant Health Cancer Institute - Kernersville
Kernersville, North Carolina, 27284
United States
Novant Health Cancer Institute - Matthews
Matthews, North Carolina, 28105
United States
Novant Health Cancer Institute - Mooresville
Mooresville, North Carolina, 28117
United States
Novant Health Cancer Institute - Mount Airy
Mount Airy, North Carolina, 27030
United States
Duke Women's Cancer Care Raleigh
Raleigh, North Carolina, 27607
United States
Novant Health Cancer Institute - Thomasville
Thomasville, North Carolina, 27360
United States
AdventHealth Infusion Center Weaverville
Weaverville, North Carolina, 28787
United States
Novant Health Forsyth Medical Center
Winston-Salem, North Carolina, 27103
United States
Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157
United States
Sanford Bismarck Medical Center
Bismarck, North Dakota, 58501
United States
Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota, 58103
United States
Sanford Broadway Medical Center
Fargo, North Dakota, 58122
United States
Sanford Roger Maris Cancer Center
Fargo, North Dakota, 58122
United States
Summa Health System - Akron Campus
Akron, Ohio, 44304
United States
Summa Health System - Barberton Campus
Barberton, Ohio, 44203
United States
Aultman Health Foundation
Canton, Ohio, 44710
United States
Miami Valley Hospital South
Centerville, Ohio, 45459
United States
University of Cincinnati Cancer Center-UC Medical Center
Cincinnati, Ohio, 45219
United States
Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio, 45220
United States
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, Ohio, 44111
United States
Cleveland Clinic Foundation
Cleveland, Ohio, 44195
United States
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210
United States
Miami Valley Hospital
Dayton, Ohio, 45409
United States
Premier Blood and Cancer Center
Dayton, Ohio, 45409
United States
Miami Valley Hospital North
Dayton, Ohio, 45415
United States
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, 45005-1066
United States
Miami Valley Cancer Care and Infusion
Greenville, Ohio, 45331
United States
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio, 44124
United States
Summa Health Medina Medical Center
Medina, Ohio, 44256
United States
ProMedica Flower Hospital
Sylvania, Ohio, 43560
United States
Upper Valley Medical Center
Troy, Ohio, 45373
United States
University of Cincinnati Cancer Center-West Chester
West Chester, Ohio, 45069
United States
Cancer Centers of Southwest Oklahoma Research
Lawton, Oklahoma, 73505
United States
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104
United States
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma, 73120
United States
Saint Alphonsus Cancer Care Center-Baker City
Baker City, Oregon, 97814
United States
Saint Charles Health System
Bend, Oregon, 97701
United States
Good Samaritan Hospital
Corvallis, Oregon, 97330
United States
Legacy Mount Hood Medical Center
Gresham, Oregon, 97030
United States
Providence Hood River Memorial Hospital
Hood River, Oregon, 97031
United States
Providence Newberg Medical Center
Newberg, Oregon, 97132
United States
Saint Alphonsus Cancer Care Center-Ontario
Ontario, Oregon, 97914
United States
Providence Willamette Falls Medical Center
Oregon City, Oregon, 97045
United States
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon, 97210
United States
Providence Portland Medical Center
Portland, Oregon, 97213
United States
Providence Saint Vincent Medical Center
Portland, Oregon, 97225
United States
Salem Hospital
Salem, Oregon, 97301
United States
Legacy Meridian Park Hospital
Tualatin, Oregon, 97062
United States
UPMC-Heritage Valley Health System Beaver
Beaver, Pennsylvania, 15009
United States
WellSpan Medical Oncology and Hematology
Chambersburg, Pennsylvania, 17201
United States
UPMC Hillman Cancer Center - Passavant - Cranberry
Cranberry Township, Pennsylvania, 16066
United States
Geisinger Medical Center
Danville, Pennsylvania, 17822
United States
Mercy Fitzgerald Hospital
Darby, Pennsylvania, 19023-1291
United States
Geisinger Cancer Center Dickson City
Dickson City, Pennsylvania, 18519
United States
Ephrata Cancer Center
Ephrata, Pennsylvania, 17522
United States
UPMC Hillman Cancer Center Erie
Erie, Pennsylvania, 16505
United States
UPMC Cancer Center at UPMC Horizon
Farrell, Pennsylvania, 16121
United States
Adams Cancer Center
Gettysburg, Pennsylvania, 17325
United States
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, Pennsylvania, 15601
United States
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Harrisburg, Pennsylvania, 17109
United States
Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, 17033-0850
United States
IRMC Cancer Center
Indiana, Pennsylvania, 15701
United States
UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown, Pennsylvania, 15901
United States
Sechler Family Cancer Center
Lebanon, Pennsylvania, 17042
United States
Geisinger Medical Oncology-Lewisburg
Lewisburg, Pennsylvania, 17837
United States
UPMC Cancer Center at UPMC McKeesport
McKeesport, Pennsylvania, 15132
United States
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
Mechanicsburg, Pennsylvania, 17050
United States
UPMC Hillman Cancer Center - Monroeville
Monroeville, Pennsylvania, 15146
United States
UPMC Hillman Cancer Center in Coraopolis
Moon Township, Pennsylvania, 15108
United States
Arnold Palmer Cancer Center Medical Oncology Norwin
N. Huntingdon, Pennsylvania, 15642
United States
UPMC Cancer Center-Natrona Heights
Natrona Heights, Pennsylvania, 15065
United States
UPMC Hillman Cancer Center - New Castle
New Castle, Pennsylvania, 16105
United States
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107
United States
Jefferson Torresdale Hospital
Philadelphia, Pennsylvania, 19114
United States
Reading Hospital McGlinn Cancer Institute at Phoenixville
Phoenixville, Pennsylvania, 19460
United States
UPMC-Magee Womens Hospital
Pittsburgh, Pennsylvania, 15213
United States
UPMC-Saint Margaret
Pittsburgh, Pennsylvania, 15215
United States
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232
United States
UPMC-Passavant Hospital
Pittsburgh, Pennsylvania, 15237
United States
UPMC-Saint Clair Hospital Cancer Center
Pittsburgh, Pennsylvania, 15243
United States
Penn State Health Saint Joseph Medical Center
Reading, Pennsylvania, 19605
United States
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania, 16346
United States
UPMC Cancer Center-Uniontown
Uniontown, Pennsylvania, 15401
United States
UPMC Cancer Center-Washington
Washington, Pennsylvania, 15301
United States
UPMC West Mifflin-Cancer Center Jefferson
West Mifflin, Pennsylvania, 15122
United States
Reading Hospital
West Reading, Pennsylvania, 19611
United States
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania, 18711
United States
Divine Providence Hospital
Williamsport, Pennsylvania, 17754
United States
Asplundh Cancer Pavilion
Willow Grove, Pennsylvania, 19090
United States
Cancer Care Associates of York
York, Pennsylvania, 17403
United States
Rhode Island Hospital
Providence, Rhode Island, 02903
United States
Women and Infants Hospital
Providence, Rhode Island, 02905
United States
Smilow Cancer Hospital Care Center - Westerly
Westerly, Rhode Island, 02891
United States
Beaufort Memorial Hospital
Beaufort, South Carolina, 29902
United States
Saint Joseph's/Candler - Bluffton Campus
Bluffton, South Carolina, 29910
United States
Prisma Health Cancer Institute - Spartanburg
Boiling Springs, South Carolina, 29316
United States
Medical University of South Carolina
Charleston, South Carolina, 29425
United States
Prisma Health Cancer Institute - Easley
Easley, South Carolina, 29640
United States
Prisma Health Cancer Institute - Butternut
Greenville, South Carolina, 29605
United States
Prisma Health Cancer Institute - Faris
Greenville, South Carolina, 29605
United States
Prisma Health Cancer Institute - Eastside
Greenville, South Carolina, 29615
United States
Self Regional Healthcare
Greenwood, South Carolina, 29646
United States
Prisma Health Cancer Institute - Greer
Greer, South Carolina, 29650
United States
South Carolina Cancer Specialists PC
Hilton Head Island, South Carolina, 29926-3827
United States
Prisma Health Cancer Institute - Seneca
Seneca, South Carolina, 29672
United States
Lexington Medical Center
West Columbia, South Carolina, 29169
United States
Rapid City Regional Hospital
Rapid City, South Dakota, 57701
United States
Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota, 57104
United States
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, 57117-5134
United States
Baptist Memorial Hospital and Cancer Center-Collierville
Collierville, Tennessee, 38017
United States
Baptist Memorial Hospital and Cancer Center-Memphis
Memphis, Tennessee, 38120
United States
Baptist Memorial Hospital for Women
Memphis, Tennessee, 38120
United States
The Don and Sybil Harrington Cancer Center
Amarillo, Texas, 79106
United States
Houston Methodist San Jacinto Hospital
Baytown, Texas, 77521
United States
MD Anderson in The Woodlands
Conroe, Texas, 77384
United States
Houston Methodist Cypress Hospital
Cypress, Texas, 77429
United States
University of Texas Medical Branch
Galveston, Texas, 77555-0565
United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas, 77030
United States
Houston Methodist Hospital
Houston, Texas, 77030
United States
M D Anderson Cancer Center
Houston, Texas, 77030
United States
Methodist Willowbrook Hospital
Houston, Texas, 77070
United States
MD Anderson West Houston
Houston, Texas, 77079
United States
Houston Methodist West Hospital
Houston, Texas, 77094
United States
MD Anderson League City
League City, Texas, 77573
United States
Houston Methodist Saint John Hospital
Nassau Bay, Texas, 77058
United States
MD Anderson in Sugar Land
Sugar Land, Texas, 77478
United States
Houston Methodist Sugar Land Hospital
Sugar Land, Texas, 77479
United States
Houston Methodist The Woodlands Hospital
The Woodlands, Texas, 77385
United States
Farmington Health Center
Farmington, Utah, 84025
United States
University of Utah Sugarhouse Health Center
Salt Lake City, Utah, 84106
United States
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112
United States
Central Vermont Medical Center/National Life Cancer Treatment
Berlin Corners, Vermont, 05602
United States
University of Vermont Medical Center
Burlington, Vermont, 05401
United States
University of Vermont and State Agricultural College
Burlington, Vermont, 05405
United States
Sentara Martha Jefferson Hospital
Charlottesville, Virginia, 22911
United States
Augusta Health Center for Cancer and Blood Disorders
Fishersville, Virginia, 22939
United States
Centra Alan B Pearson Regional Cancer Center
Lynchburg, Virginia, 24501
United States
Kaiser Permanente Tysons Corner Medical Center
McLean, Virginia, 22102
United States
Bon Secours Memorial Regional Medical Center
Mechanicsville, Virginia, 23116
United States
Bon Secours Saint Francis Medical Center
Midlothian, Virginia, 23114
United States
Bon Secours Saint Mary's Hospital
Richmond, Virginia, 23226
United States
Virginia Cancer Institute
Richmond, Virginia, 23229
United States
VCU Massey Comprehensive Cancer Center
Richmond, Virginia, 23298
United States
VCU Community Memorial Health Center
South Hill, Virginia, 23970
United States
Shenandoah Oncology PC
Winchester, Virginia, 22601
United States
Kaiser Permanente-Caton Hill Medical Center
Woodbridge, Virginia, 22192
United States
FHCC Overlake
Bellevue, Washington, 98004
United States
Swedish Cancer Institute-Edmonds
Edmonds, Washington, 98026
United States
Swedish Cancer Institute-Issaquah
Issaquah, Washington, 98029
United States
Kadlec Clinic Hematology and Oncology
Kennewick, Washington, 99336
United States
FHCC at EvergreenHealth
Kirkland, Washington, 98034
United States
Skagit Regional Health Cancer Care Center
Mount Vernon, Washington, 98274
United States
Fred Hutchinson Cancer Center
Seattle, Washington, 98109
United States
Swedish Medical Center-First Hill
Seattle, Washington, 98122
United States
FHCC at Northwest Hospital
Seattle, Washington, 98133
United States
Cancer Care Northwest - Spokane South
Spokane, Washington, 99202
United States
Cancer Care Northwest-Valley
Spokane, Washington, 99216
United States
Cancer Care Northwest-North Spokane
Spokane, Washington, 99218
United States
Legacy Cancer Institute Medical Oncology and Day Treatment
Vancouver, Washington, 98684
United States
Legacy Salmon Creek Hospital
Vancouver, Washington, 98686
United States
Providence Saint Mary Regional Cancer Center
Walla Walla, Washington, 99362
United States
West Virginia University Healthcare
Morgantown, West Virginia, 26506
United States
Camden Clark Medical Center
Parkersburg, West Virginia, 26101
United States
Princeton Community Hospital
Princeton, West Virginia, 24740
United States
Wheeling Hospital/Schiffler Cancer Center
Wheeling, West Virginia, 26003
United States
Langlade Hospital and Cancer Center
Antigo, Wisconsin, 54409
United States
ThedaCare Regional Cancer Center
Appleton, Wisconsin, 54911
United States
Ascension Saint Elizabeth Hospital
Appleton, Wisconsin, 54915
United States
Duluth Clinic Ashland
Ashland, Wisconsin, 54806
United States
Northwest Wisconsin Cancer Center
Ashland, Wisconsin, 54806
United States
Ascension Southeast Wisconsin Hospital - Elmbrook Campus
Brookfield, Wisconsin, 53045
United States
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin, 53105
United States
Ascension Calumet Hospital
Chilton, Wisconsin, 53014
United States
Aurora Saint Luke's South Shore
Cudahy, Wisconsin, 53110
United States
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin, 54701
United States
Mayo Clinic Health System-Eau Claire Clinic
Eau Claire, Wisconsin, 54701
United States
Ascension Saint Francis - Reiman Cancer Center
Franklin, Wisconsin, 53132
United States
Aurora Health Care Germantown Health Center
Germantown, Wisconsin, 53022
United States
Aurora Cancer Care-Grafton
Grafton, Wisconsin, 53024
United States
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin, 54301
United States
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin, 54303
United States
Aurora BayCare Medical Center
Green Bay, Wisconsin, 54311
United States
Essentia Health-Hayward Clinic
Hayward, Wisconsin, 54843
United States
University of Wisconsin Carbone Cancer Center - Johnson Creek
Johnson Creek, Wisconsin, 53038
United States
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin, 53142
United States
Mayo Clinic Health System-Franciscan Healthcare
La Crosse, Wisconsin, 54601
United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, Wisconsin, 53718
United States
University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792
United States
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin, 54143
United States
Aspirus Medford Hospital
Medford, Wisconsin, 54451
United States
Froedtert Menomonee Falls Hospital
Menomonee Falls, Wisconsin, 53051
United States
Ascension Columbia Saint Mary's Hospital Ozaukee
Mequon, Wisconsin, 53097
United States
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin, 53209
United States
Ascension Columbia Saint Mary's Hospital - Milwaukee
Milwaukee, Wisconsin, 53211
United States
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, 53215
United States
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
United States
Aurora Sinai Medical Center
Milwaukee, Wisconsin, 53233
United States
ProHealth D N Greenwald Center
Mukwonago, Wisconsin, 53149
United States
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, 54017
United States
Drexel Town Square Health Center
Oak Creek, Wisconsin, 53154
United States
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin, 53066
United States
Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls, Wisconsin, 54154
United States
Ascension Mercy Hospital
Oshkosh, Wisconsin, 54904
United States
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, 54904
United States
Ascension All Saints Hospital
Racine, Wisconsin, 53405
United States
Aurora Cancer Care-Racine
Racine, Wisconsin, 53406
United States
Aspirus Cancer Care - James Beck Cancer Center
Rhinelander, Wisconsin, 54501
United States
Saint Vincent Hospital Cancer Center at Sheboygan
Sheboygan, Wisconsin, 53081
United States
Sheboygan Physicians Group
Sheboygan, Wisconsin, 53081
United States
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, 53081
United States
Aspirus Cancer Care - Stevens Point
Stevens Point, Wisconsin, 54481
United States
Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin, 54482
United States
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin, 54235-1495
United States
Aurora Medical Center in Summit
Summit, Wisconsin, 53066
United States
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin, 54241
United States
ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin, 53188
United States
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin, 53188
United States
Aspirus Regional Cancer Center
Wausau, Wisconsin, 54401
United States
Ascension Medical Group Southeast Wisconsin - Mayfair Road
Wauwatosa, Wisconsin, 53226
United States
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin, 53226
United States
Aurora West Allis Medical Center
West Allis, Wisconsin, 53227
United States
Froedtert West Bend Hospital/Kraemer Cancer Center
West Bend, Wisconsin, 53095
United States
Marshfield Medical Center - Weston
Weston, Wisconsin, 54476
United States
Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids, Wisconsin, 54494
United States

Collaborators and Investigators

Sponsor: Alliance for Clinical Trials in Oncology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-19
Study Completion Date2031-11-30

Study Record Updates

Study Start Date2025-02-19
Study Completion Date2031-11-30

Terms related to this study

Additional Relevant MeSH Terms

  • Anatomic Stage 0 Breast Cancer AJCC v8
  • Anatomic Stage 1 Breast Cancer AJCC v8
  • Anatomic Stage IIA Breast Cancer AJCC v8
  • Estrogen Receptor-Positive Breast Carcinoma
  • HER2-Negative Breast Carcinoma