This study is open to people with cirrhosis caused by a liver disease called MASH (metabolic dysfunction-associated steatohepatitis). The purpose of this study is to find out how well a medicine called BI 770371 is tolerated. Participants are put into 2 groups by chance. One group gets BI 770371 as an infusion into a vein and the other group gets placebo as an infusion into a vein. Placebo infusions look like BI 770371 infusions but do not contain any medicine. Participants get an infusion every 3 weeks for 12 weeks. Participants are in the study for about 5 months. During this time, they visit the study site 16 times. This also includes 1 overnight stay at the study site. The doctors regularly check participants' health and collect information on any health problems of the participants. The results are compared between the 2 groups.
Compensated Liver Cirrhosis, Metabolic Dysfunction Associated Steatohepatitis (MASH)
This study is open to people with cirrhosis caused by a liver disease called MASH (metabolic dysfunction-associated steatohepatitis). The purpose of this study is to find out how well a medicine called BI 770371 is tolerated. Participants are put into 2 groups by chance. One group gets BI 770371 as an infusion into a vein and the other group gets placebo as an infusion into a vein. Placebo infusions look like BI 770371 infusions but do not contain any medicine. Participants get an infusion every 3 weeks for 12 weeks. Participants are in the study for about 5 months. During this time, they visit the study site 16 times. This also includes 1 overnight stay at the study site. The doctors regularly check participants' health and collect information on any health problems of the participants. The results are compared between the 2 groups.
A Study to Test How Well BI 770371 is Tolerated by People With Cirrhosis Caused by a Liver Disease Called MASH
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Southern California Research Center, Coronado, California, United States, 92118
Catalina Research Institute, LLC-Montclair-49051, Montclair, California, United States, 91763
Inland Empire Clinical Trials, LLC, Rialto, California, United States, 92377
Peak Gastroenterology Associates-Colorado Springs-67762, Colorado Springs, Colorado, United States, 80907
The Liver Institute at Methodist Dallas, Dallas, Texas, United States, 75203
Houston Research Institute, Houston, Texas, United States, 77079
American Research Corporation at the Texas Liver Institute, San Antonio, Texas, United States, 78215
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to 75 Years
ALL
No
Boehringer Ingelheim,
2025-12-29