Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Surgical candidate for complete hysterectomy and bilateral salpingooophorectomy with pelvic and aortic lymphadenectomy
- * Histologically or cytologically confirmed carcinoma of the endometrium confined to the uterine corpus
- * No clinical evidence of extra-uterine disease on pre-operative evaluation. Preoperative evaluation to rule-out extra-uterine disease may include a CT scan, MRI or ultrasound. Note: preoperative imaging is not mandatory for study enrollment.
- * Prior systemic chemotherapy is allowed so long as it was at least five years prior to study enrollment, and there is no evidence of disease after such therapy.
- * Life expectancy (estimated survival) of at least 6 months.
- * AST(SGOT)/ALT(SGPT) \< 3.0X upper limit of normal
- * Ability to understand and the willingness to sign a written informed consent document
- * GOG Performance Status greater than 2 (Appendix II)
- * Uterine sarcoma
- * Clinical evidence of disease that extends beyond the uterus, including the presence of suspicious aortic or inguinal nodes on imaging or clinical exam
- * Previous vaginal, pelvic or abdominal irradiation
- * Chemotherapy, hormone therapy or immunotherapy directed at the present disease
- * Previous pelvic lymphadenectomy or retroperitoneal surgery
- * Patients with a prior or concurrent malignancy whose natural history or treatment has the potential to interfere with the safety or efficacy assessment of the investigational regimen should be excluded
- * Known allergy to iodine or indocyanine green (ICG) tracer, or allergic reactions to compounds of similar chemical or biologic composition
- * Patients with uncontrolled intercurrent illness
- * Patients with psychiatric illness/social situations that would limit compliance with study requirements
- * Pregnant or lactating women. Women of child-bearing potential will be excluded if they have a positive serum/urine pregnancy test
Ages Eligible for Study
18 Years to
Sexes Eligible for Study
FEMALE
Accepts Healthy Volunteers
No