Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing

Description

The primary purpose of this study is to perform a high-quality randomized control trial comparing intramedullary tibial nail fixation with standard design nails to a micromotion tibial nail device, to evaluate the rates of union and post-operative outcomes.

Conditions

Tibial Fractures

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Study Overview

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Study Details

Study overview

The primary purpose of this study is to perform a high-quality randomized control trial comparing intramedullary tibial nail fixation with standard design nails to a micromotion tibial nail device, to evaluate the rates of union and post-operative outcomes.

Comparison of Healing Measures in Diaphyseal Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing

Comparison of Healing Measures Tibial Fractures Following Standard Intramedullary Nailing or Micromotion Tibial Intramedullary Nailing

Condition
Tibial Fractures
Intervention / Treatment

-

Contacts and Locations

Birmingham

University of Alabama at Birmingham Main Hospital, Birmingham, Alabama, United States, 35294

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18 - 85 years
  • * Stable Tibial fracture recommended for surgical intervention
  • * Patients not meeting inclusion criteria
  • * Unstable fracture patterns e.g. those needing a secondary intervention - masquelet/cement spacer)
  • * Previously non-ambulatory patients
  • * Delayed presentation of fracture (\>4 weeks)
  • * Fractures that the treating surgeon indicates requires additional fixation strategies to achieve stability
  • * Patients with an achieve infection or wound at the surgical site
  • * Any previous ligament or fracture surgery on the index site
  • * Inflammatory rheumatic disease or other rheumatic disease-
  • * Immune compromised patients (hepatitis, HIV, etc.)
  • * Unwilling or unable to participate or follow study protocol

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Alabama at Birmingham,

Joseph Johnson, MD, PRINCIPAL_INVESTIGATOR, University of Alabama at Birmingham

Study Record Dates

2026-12-01