RECRUITING

Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

the investigators will pursue two specific aims: (1) to monitor the extent of heme oxygenase induction (by measuring endogenous CO production) in relationship to the extent of hepatic resection (2) to assess the production of CO in patients following liver resection and correlate these findings to the rate of liver regeneration and liver function.

Official Title

Postoperative Heme Oxygenase Induction and Carbon Monoxide Production as a Novel Method to Assess Hepatic Regeneration and Predict Hepatic Related Morbidity After Partial Hepatectomy

Quick Facts

Study Start:2025-11-21
Study Completion:2039-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06681818

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patient plans to have partial liver resection for primary liver pathology or metastatic disease
  2. * Patient is able to comprehend and willing to sign the written consent form
  1. * Patients \< 18 years
  2. * Patients identified as members of a vulnerable population, except women of child bearing potential with negative pregnancy test

Contacts and Locations

Study Contact

Jamie Ketas
CONTACT
2018943418
jamie.ketas@ehmchealth.org
Raquel Molina
CONTACT
raquel.molina@ehmchealth.org

Principal Investigator

Cherif Boutros, MD
PRINCIPAL_INVESTIGATOR
Englewood Hospital

Study Locations (Sites)

Englewood Hospital
Englewood, New Jersey, 07631
United States

Collaborators and Investigators

Sponsor: Englewood Hospital and Medical Center

  • Cherif Boutros, MD, PRINCIPAL_INVESTIGATOR, Englewood Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-11-21
Study Completion Date2039-01-01

Study Record Updates

Study Start Date2025-11-21
Study Completion Date2039-01-01

Terms related to this study

Keywords Provided by Researchers

  • hepatectomy

Additional Relevant MeSH Terms

  • Liver Cancer Adult
  • Liver Regeneration