Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy

Description

This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA). We are doing the research to investigate the effects of extracorporeal shockwave therapy (ESWT) on pain, function, biomechanics, knee range of motion and strength, inflammation, and joint structure and integrity of the knee.

Conditions

Knee Osteoarthristis, ACL Injuries, Post-Traumatic

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Study Overview

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Study Details

Study overview

This study is recruiting current or former athletes who had ACL reconstruction surgery over a year ago and have been diagnosed with knee osteoarthritis (OA). We are doing the research to investigate the effects of extracorporeal shockwave therapy (ESWT) on pain, function, biomechanics, knee range of motion and strength, inflammation, and joint structure and integrity of the knee.

Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy

Treatment of Post Traumatic Knee Osteoarthritis With Extracorporeal Shockwave Therapy

Condition
Knee Osteoarthristis
Intervention / Treatment

-

Contacts and Locations

Cambridge

Spaulding Cambridge Hospital, Cambridge, Massachusetts, United States, 02138

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of mild to moderate PTOA based on clinical diagnosis and confirmation with radiographic evidence by a medical professional prior to study enrollment
  • * Previous ACL reconstruction using patellar-tendon-bone autograft in the knee with PTOA
  • * Minimum of one year following ACL reconstruction surgery
  • * Between ages of 18 and 55
  • * No clear contraindication to complete protocol including mechanical symptoms which would limit ability to complete the study
  • * Score on KOOS pain subscale of \< 72
  • * Primary pain is coming from the knee
  • * Have previously received injections to the knee joint within the past 3 months
  • * Women who are pregnant or those who are planning to become pregnant. This is due to the fact that pregnancy will reduce participants activity after the treatment and the safety concerns related to shockwave treatment. - Participants with neuropathy affecting sensation to pain
  • * Participants with a known underlying cardiac disease that could be affected by shockwave therapy
  • * Chronic rheumatological conditions, immunodeficiency, severe asthma, connective tissue disorder (i.e. Ehlers-Danlos Syndrome), or other medical conditions (ex. active malignancy, severe asthma) outside of PTOA that are known to impact inflammatory state or requiring chronic use of oral or intravenous immune modulatory medications. Asthma requiring use of inhalers only is not an exclusion criteria
  • * Neuropathy diagnosis that can affect response to pain
  • * No active use of oral steroids or anti-inflammatories at the time of enrollment
  • * Have bilateral ACL injury or reconstruction surgery, or have had ACL revision surgery
  • * No active malignancy and at least five years in remission
  • * Previous ESWT treatment using study treatment devices for management of knee osteoarthritis
  • * Have a pacemaker, bone screws, or any other metal implants that would prohibit participation in an MRI scan or EWST
  • * Non-English speaking individuals

Ages Eligible for Study

18 Years to 55 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Spaulding Rehabilitation Hospital,

Study Record Dates

2026-09